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    PLA2G7 phospholipase A2 group VII [ Bos taurus (domestic cattle) ]

    Gene ID: 282311, updated on 30-Jan-2025

    Summary

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    Official Symbol
    PLA2G7provided by VGNC
    Official Full Name
    phospholipase A2 group VIIprovided by VGNC
    Primary source
    VGNC:VGNC:32965
    See related
    BGD:BT24959; EnsemblRapid:ENSBTAG00070031101
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PLA2G7 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (19925027..19963288, complement)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 member 27 Neighboring gene tudor domain containing 6 Neighboring gene ankyrin repeat domain 66 Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene meprin A subunit alpha

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Anti-inflammatory properties of a platelet-activating factor acetylhydrolase. Tjoelker LW, et al. Nature, 1995 Apr 6. PMID 7700381
    2. Plasma platelet-activating factor acetylhydrolase is a secreted phospholipase A2 with a catalytic triad. Tjoelker LW, et al. J Biol Chem, 1995 Oct 27. PMID 7592717
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-alkyl-2-acetylglycerophosphocholine esterase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    platelet-activating factor acetylhydrolase
    Names
    1-alkyl-2-acetylglycerophosphocholine esterase
    2-acetyl-1-alkylglycerophosphocholine esterase
    LDL-PLA(2)
    LDL-associated phospholipase A2
    PAF 2-acylhydrolase
    PAF acetylhydrolase
    phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
    NP_777003.2
    XP_005223433.1
    XP_005223434.1
    XP_005223435.1
    XP_005223436.1
    XP_010816468.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174578.4 → NP_777003.2  platelet-activating factor acetylhydrolase precursor

      See identical proteins and their annotated locations for NP_777003.2

      Status: PROVISIONAL

      Source sequence(s)
      BC114827
      UniProtKB/Swiss-Prot
      Q28017
      UniProtKB/TrEMBL
      Q1RML9
      Related
      ENSBTAP00070042916.1, ENSBTAT00070070465.1
      Conserved Domains (1) summary
      pfam03403
      Location:52 → 417
      PAF-AH_p_II; Platelet-activating factor acetylhydrolase, isoform II

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      19925027..19963288 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005223376.4 → XP_005223433.1  platelet-activating factor acetylhydrolase isoform X1

      See identical proteins and their annotated locations for XP_005223433.1

      UniProtKB/Swiss-Prot
      Q28017
      UniProtKB/TrEMBL
      Q1RML9
      Conserved Domains (1) summary
      pfam03403
      Location:52 → 417
      PAF-AH_p_II; Platelet-activating factor acetylhydrolase, isoform II

    2. XM_005223379.5 → XP_005223436.1  platelet-activating factor acetylhydrolase isoform X2

      See identical proteins and their annotated locations for XP_005223436.1

      UniProtKB/Swiss-Prot
      Q28017
      Conserved Domains (1) summary
      pfam03403
      Location:7 → 372
      PAF-AH_p_II; Platelet-activating factor acetylhydrolase, isoform II

    3. XM_005223378.5 → XP_005223435.1  platelet-activating factor acetylhydrolase isoform X2

      See identical proteins and their annotated locations for XP_005223435.1

      UniProtKB/Swiss-Prot
      Q28017
      Conserved Domains (1) summary
      pfam03403
      Location:7 → 372
      PAF-AH_p_II; Platelet-activating factor acetylhydrolase, isoform II

    4. XM_005223377.4 → XP_005223434.1  platelet-activating factor acetylhydrolase isoform X1

      See identical proteins and their annotated locations for XP_005223434.1

      UniProtKB/Swiss-Prot
      Q28017
      UniProtKB/TrEMBL
      Q1RML9
      Conserved Domains (1) summary
      pfam03403
      Location:52 → 417
      PAF-AH_p_II; Platelet-activating factor acetylhydrolase, isoform II

    5. XM_010818166.3 → XP_010816468.1  platelet-activating factor acetylhydrolase isoform X1

      See identical proteins and their annotated locations for XP_010816468.1

      UniProtKB/Swiss-Prot
      Q28017
      UniProtKB/TrEMBL
      Q1RML9
      Conserved Domains (1) summary
      pfam03403
      Location:52 → 417
      PAF-AH_p_II; Platelet-activating factor acetylhydrolase, isoform II
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q28017.1 GenPept UniProtKB/Swiss-Prot:Q28017

    Gene LinkOut

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