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    ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 615368, updated on 1-Jan-2025

    Summary

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    Official Symbol
    ORMDL3provided by VGNC
    Official Full Name
    ORMDL sphingolipid biosynthesis regulator 3provided by VGNC
    Primary source
    VGNC:VGNC:32454
    See related
    BGD:BT25418; Ensembl:ENSBTAG00000013855
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ORMDL3 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (40256165..40263411, complement)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene zona pellucida binding protein 2 Neighboring gene uncharacterized LOC112442664 Neighboring gene gasdermin B Neighboring gene leucine rich repeat containing 3C Neighboring gene gasdermin A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in ceramide metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular sphingolipid homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sphingolipid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ORM1-like protein 3
    Names
    ORM1-like 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076367.1 → NP_001069835.1  ORM1-like protein 3

      Status: PROVISIONAL

      Source sequence(s)
      BC119888
      UniProtKB/Swiss-Prot
      Q0VD15
      UniProtKB/TrEMBL
      A0AAF6YZM1
      Related
      ENSBTAP00000018402.4, ENSBTAT00000018402.5
      Conserved Domains (1) summary
      pfam04061
      Location:11 → 146
      ORMDL; ORMDL family

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      40256165..40263411 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024980425.2 → XP_024836193.1  ORM1-like protein 3 isoform X1

      UniProtKB/Swiss-Prot
      Q0VD15
      UniProtKB/TrEMBL
      A0AAF6YZM1
      Conserved Domains (1) summary
      pfam04061
      Location:11 → 146
      ORMDL; ORMDL family

    2. XM_005220755.5 → XP_005220812.1  ORM1-like protein 3 isoform X1

      UniProtKB/Swiss-Prot
      Q0VD15
      UniProtKB/TrEMBL
      A0AAF6YZM1
      Conserved Domains (1) summary
      pfam04061
      Location:11 → 146
      ORMDL; ORMDL family

    3. XM_005220754.5 → XP_005220811.1  ORM1-like protein 3 isoform X1

      UniProtKB/Swiss-Prot
      Q0VD15
      UniProtKB/TrEMBL
      A0AAF6YZM1
      Conserved Domains (1) summary
      pfam04061
      Location:11 → 146
      ORMDL; ORMDL family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0VD15.1 GenPept UniProtKB/Swiss-Prot:Q0VD15

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