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    TGFBRAP1 transforming growth factor beta receptor associated protein 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 514660, updated on 30-Jan-2025

    Summary

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    Official Symbol
    TGFBRAP1provided by VGNC
    Official Full Name
    transforming growth factor beta receptor associated protein 1provided by VGNC
    Primary source
    VGNC:VGNC:35806
    See related
    BGD:BT25700; EnsemblRapid:ENSBTAG00070035916
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    TRAP1; TRAP-1
    Orthologs
    human mouse all
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    Genomic context

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    See TGFBRAP1 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (9215833..9249652, complement)

    Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein S9 Neighboring gene G protein-coupled receptor 45 Neighboring gene uncharacterized LOC100848208 Neighboring gene chromosome 11 C2orf49 homolog

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC152624

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in autophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in endosomal vesicle fusion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transforming growth factor-beta receptor-associated protein 1
    Names
    TGF-beta receptor-associated protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102008.1 → NP_001095478.1  transforming growth factor-beta receptor-associated protein 1

      See identical proteins and their annotated locations for NP_001095478.1

      Status: PROVISIONAL

      Source sequence(s)
      BC151278
      UniProtKB/Swiss-Prot
      A7MB11
      UniProtKB/TrEMBL
      F1MWF9
      Related
      ENSBTAP00070048761.1, ENSBTAT00070080511.1
      Conserved Domains (4) summary
      pfam00637
      Location:574 → 699
      Clathrin; Region in Clathrin and VPS
      pfam10366
      Location:448 → 550
      Vps39_1; Vacuolar sorting protein 39 domain 1
      pfam10367
      Location:737 → 845
      Vps39_2; Vacuolar sorting protein 39 domain 2
      cl02434
      Location:34 → 283
      CNH; CNH domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      9215833..9249652 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024998576.2 → XP_024854344.1  transforming growth factor-beta receptor-associated protein 1 isoform X1

      UniProtKB/TrEMBL
      F1MWF9
      Conserved Domains (4) summary
      pfam00637
      Location:681 → 795
      Clathrin; Region in Clathrin and VPS
      pfam10366
      Location:545 → 647
      Vps39_1; Vacuolar sorting protein 39 domain 1
      pfam10367
      Location:834 → 942
      Vps39_2; Vacuolar sorting protein 39 domain 2
      cl02434
      Location:34 → 283
      CNH; CNH domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A7MB11.1 GenPept UniProtKB/Swiss-Prot:A7MB11

    Gene LinkOut

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