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    BRD2 bromodomain containing 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 505358, updated on 27-Dec-2024

    Summary

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    Official Symbol
    BRD2provided by VGNC
    Official Full Name
    bromodomain containing 2provided by VGNC
    Primary source
    VGNC:VGNC:26557
    See related
    BGD:BT11370; Ensembl:ENSBTAG00000011074
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See BRD2 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (7285030..7294765)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene major histocompatibility complex, class II, DM beta Neighboring gene major histocompatibility complex, class II, DM alpha Neighboring gene major histocompatibility complex, class II, DO alpha Neighboring gene collagen type XI alpha 2 chain Neighboring gene uncharacterized LOC132343598

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Comparative analysis of the bovine MHC class IIb sequence identifies inversion breakpoints and three unexpected genes. Childers CP, et al. Anim Genet, 2006 Apr. PMID 16573526
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables lysine-acetylated histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    bromodomain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045866.1 → NP_001039331.1  bromodomain-containing protein 2

      Status: PROVISIONAL

      Source sequence(s)
      AY957499
      UniProtKB/Swiss-Prot
      Q32S26
      UniProtKB/TrEMBL
      A0AAA9SV13
      Related
      ENSBTAP00000014704.5, ENSBTAT00000014704.7
      Conserved Domains (4) summary
      cd05497
      Location:74 → 180
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:349 → 450
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:216 → 333
      PHA03247; large tegument protein UL36; Provisional
      pfam17035
      Location:643 → 705
      BET; Bromodomain extra-terminal - transcription regulation

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      7285030..7294765
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024983436.2 → XP_024839204.1  bromodomain-containing protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q32S26
      UniProtKB/TrEMBL
      A0AAA9SV13
      Conserved Domains (4) summary
      cd05497
      Location:74 → 180
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:349 → 450
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:216 → 333
      PHA03247; large tegument protein UL36; Provisional
      pfam17035
      Location:643 → 705
      BET; Bromodomain extra-terminal - transcription regulation

    2. XM_015459719.3 → XP_015315205.1  bromodomain-containing protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q32S26
      UniProtKB/TrEMBL
      A0AAA9SV13
      Conserved Domains (4) summary
      cd05497
      Location:74 → 180
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:349 → 450
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:216 → 333
      PHA03247; large tegument protein UL36; Provisional
      pfam17035
      Location:643 → 705
      BET; Bromodomain extra-terminal - transcription regulation

    3. XM_005223211.5 → XP_005223268.1  bromodomain-containing protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q32S26
      UniProtKB/TrEMBL
      A0AAA9SV13
      Related
      ENSBTAP00000087806.1, ENSBTAT00000091796.1
      Conserved Domains (4) summary
      cd05497
      Location:74 → 180
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:349 → 450
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      PHA03247
      Location:216 → 333
      PHA03247; large tegument protein UL36; Provisional
      pfam17035
      Location:643 → 705
      BET; Bromodomain extra-terminal - transcription regulation

    4. XM_059880240.1 → XP_059736223.1  bromodomain-containing protein 2 isoform X3

      UniProtKB/TrEMBL
      A0AAA9SV13

    5. XM_024983437.2 → XP_024839205.1  bromodomain-containing protein 2 isoform X2

      UniProtKB/TrEMBL
      A0AAA9SV13
      Conserved Domains (4) summary
      cd05497
      Location:27 → 133
      Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      cd05498
      Location:302 → 403
      Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
      pfam17035
      Location:596 → 658
      BET; Bromodomain extra-terminal - transcription regulation
      cl26464
      Location:169 → 286
      Atrophin-1; Atrophin-1 family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q32S26.1 GenPept UniProtKB/Swiss-Prot:Q32S26

    Gene LinkOut

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    Research Materials