U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PPP2R2A protein phosphatase 2 regulatory subunit Balpha [ Bos taurus (domestic cattle) ]

    Gene ID: 508045, updated on 29-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    PPP2R2Aprovided by VGNC
    Official Full Name
    protein phosphatase 2 regulatory subunit Balphaprovided by VGNC
    Primary source
    VGNC:VGNC:33255
    See related
    BGD:BT15741; Ensembl:ENSBTAG00000018317
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PPP2R2A in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 8 NC_037335.1 (73542117..73620437)

    Chromosome 8 - NC_037335.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101907345 Neighboring gene uncharacterized LOC104969415 Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene BCL2 interacting protein 3 like Neighboring gene PNMA family member 2

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037335.1 Chromosome 8 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein phosphatase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of protein phosphatase type 2A complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform
    Names
    protein phosphatase 2, regulatory subunit B, alpha
    NP_001178462.1
    XP_010806368.1
    XP_024851314.1
    XP_059744983.1
    XP_059744984.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191533.1 → NP_001178462.1  serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

      See identical proteins and their annotated locations for NP_001178462.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000008
      UniProtKB/TrEMBL
      A0AAA9SUN4
      Related
      ENSBTAP00070037243.1, ENSBTAT00070062375.1
      Conserved Domains (2) summary
      COG5170
      Location:17 → 452
      CDC55; Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms]
      sd00039
      Location:41 → 89
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037335.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      73542117..73620437
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024995546.2 → XP_024851314.1  serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X1

      UniProtKB/TrEMBL
      A0AAA9SUN4, A0AAA9SXD4
      Related
      ENSBTAP00070037250.1, ENSBTAT00070062384.1
      Conserved Domains (2) summary
      COG5170
      Location:7 → 442
      CDC55; Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms]
      sd00039
      Location:31 → 79
      7WD40; WD40 repeat [structural motif]

    2. XM_059889001.1 → XP_059744984.1  serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X3

      UniProtKB/TrEMBL
      A0A3Q1MVS3
      Related
      ENSBTAP00070037225.1, ENSBTAT00070062355.1

    3. XM_059889000.1 → XP_059744983.1  serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X2

      UniProtKB/TrEMBL
      A0AAA9TTP1
      Related
      ENSBTAP00070037193.1, ENSBTAT00070062318.1

    4. XM_010808066.4 → XP_010806368.1  serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X4

      See identical proteins and their annotated locations for XP_010806368.1

      Conserved Domains (2) summary
      COG5170
      Location:2 → 283
      CDC55; Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms]
      sd00039
      Location:21 → 57
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials