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    MMP23 matrix metallopeptidase 23 [ Bos taurus (domestic cattle) ]

    Gene ID: 527590, updated on 30-Jan-2025

    Summary

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    Official Symbol
    MMP23provided by VGNC
    Official Full Name
    matrix metallopeptidase 23provided by VGNC
    Primary source
    VGNC:VGNC:53594
    See related
    BGD:BT10542; EnsemblRapid:ENSBTAG00070021140
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    MMP23B
    Orthologs
    human mouse all
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    Genomic context

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    See MMP23 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 16 NC_037343.1 (51003855..51006199, complement)

    Chromosome 16 - NC_037343.1Genomic Context describing neighboring genes Neighboring gene NAD kinase Neighboring gene solute carrier family 35 member E2B Neighboring gene cyclin dependent kinase 11B Neighboring gene large ribosomal subunit protein P1 Neighboring gene MIB E3 ubiquitin protein ligase 2 Neighboring gene large ribosomal subunit protein eL39-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037343.1 Chromosome 16 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC134522

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in collagen catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    matrix metalloproteinase-23
    Names
    MMP-23
    matrix metallopeptidase 23B
    matrix metalloproteinase 23B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001038556.2 → NP_001033645.1  matrix metalloproteinase-23

      See identical proteins and their annotated locations for NP_001033645.1

      Status: PROVISIONAL

      Source sequence(s)
      BC109902
      UniProtKB/Swiss-Prot
      Q2TBM7
      UniProtKB/TrEMBL
      F1N5K7
      Related
      ENSBTAP00070028550.1, ENSBTAT00070047707.1
      Conserved Domains (5) summary
      smart00408
      Location:316 → 376
      IGc2; Immunoglobulin C-2 Type
      smart00254
      Location:258 → 292
      ShKT; ShK toxin domain
      smart00410
      Location:310 → 376
      IG_like; Immunoglobulin like
      cd04278
      Location:90 → 257
      ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
      pfam00413
      Location:90 → 257
      Peptidase_M10; Matrixin

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037343.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      51003855..51006199 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005217096.5 → XP_005217153.1  matrix metalloproteinase-23 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1M729, F1N5K7
      Related
      ENSBTAP00070028560.1, ENSBTAT00070047723.1
      Conserved Domains (2) summary
      smart00254
      Location:258 → 292
      ShKT; ShK toxin domain
      cd04278
      Location:90 → 257
      ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2TBM7.1 GenPept UniProtKB/Swiss-Prot:Q2TBM7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.