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    PKN3 protein kinase N3 [ Bos taurus (domestic cattle) ]

    Gene ID: 505353, updated on 1-Jan-2025

    Summary

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    Official Symbol
    PKN3provided by VGNC
    Official Full Name
    protein kinase N3provided by VGNC
    Primary source
    VGNC:VGNC:32947
    See related
    Ensembl:ENSBTAG00000010195
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PKN3 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (99211376..99224634)

    Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene spectrin alpha, non-erythrocytic 1 Neighboring gene dynein 2 intermediate chain 2 Neighboring gene SET nuclear proto-oncogene Neighboring gene uncharacterized LOC101908339 Neighboring gene zinc finger DHHC-type palmitoyltransferase 12 Neighboring gene zyg-11 related cell cycle regulator Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase N3
    NP_001192495.1
    XP_010808695.1
    XP_010808696.1
    XP_015329096.1
    XP_059747051.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205566.1 → NP_001192495.1  serine/threonine-protein kinase N3

      See identical proteins and their annotated locations for NP_001192495.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000011
      UniProtKB/TrEMBL
      A0A3Q1LM61
      Related
      ENSBTAP00000057930.1, ENSBTAT00000075730.2
      Conserved Domains (5) summary
      PTZ00263
      Location:555 → 879
      PTZ00263; protein kinase A catalytic subunit; Provisional
      cd11622
      Location:14 → 78
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd05589
      Location:559 → 884
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl00087
      Location:97 → 170
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
      cl14603
      Location:328 → 410
      C2; C2 domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      99211376..99224634
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015473610.3 → XP_015329096.1  serine/threonine-protein kinase N3 isoform X4

      Conserved Domains (5) summary
      cd11622
      Location:14 → 78
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      smart00220
      Location:559 → 805
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl00087
      Location:97 → 170
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
      cl14603
      Location:328 → 410
      C2; C2 domain
      cl21453
      Location:559 → 809
      PKc_like; Protein Kinases, catalytic domain

    2. XM_010810394.4 → XP_010808696.1  serine/threonine-protein kinase N3 isoform X2

      Conserved Domains (5) summary
      PTZ00263
      Location:551 → 875
      PTZ00263; protein kinase A catalytic subunit; Provisional
      cd11622
      Location:14 → 78
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd05589
      Location:555 → 880
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl00087
      Location:97 → 170
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
      cl14603
      Location:324 → 406
      C2; C2 domain

    3. XM_059891068.1 → XP_059747051.1  serine/threonine-protein kinase N3 isoform X3

    4. XM_010810393.4 → XP_010808695.1  serine/threonine-protein kinase N3 isoform X1

      UniProtKB/TrEMBL
      E1B7J3
      Related
      ENSBTAP00000013461.5, ENSBTAT00000013461.6
      Conserved Domains (6) summary
      PTZ00263
      Location:552 → 876
      PTZ00263; protein kinase A catalytic subunit; Provisional
      cd11622
      Location:11 → 75
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11637
      Location:167 → 227
      HR1_PKN3_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N3
      cd05589
      Location:556 → 881
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl00087
      Location:94 → 167
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
      cl14603
      Location:325 → 407
      C2; C2 domain
    Nucleotide Protein Strain
    Heading Accession and Version

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