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    SLC11A2 solute carrier family 11 member 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 521189, updated on 30-Jan-2025

    Summary

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    Gene symbol
    SLC11A2
    Gene description
    solute carrier family 11 member 2
    See related
    BGD:BT13058; EnsemblRapid:ENSBTAG00070037462
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
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    Genomic context

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    See SLC11A2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (28722064..28757980)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene cysteine and serine rich nuclear protein 2 Neighboring gene uncharacterized LOC112446676 Neighboring gene LETM1 domain containing 1 Neighboring gene N6-adenosine-methyltransferase TMT1A-like Neighboring gene small nucleolar RNA SNORA38

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cadmium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cadmium ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cobalt ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ferrous iron transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables lead ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables manganese ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nickel cation transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in iron import into cell IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organismal-level iron ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to hypoxia IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apical part of cell IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in early endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in late endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lysosomal membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in recycling endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    natural resistance-associated macrophage protein 2
    Names
    solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001101103.1 → NP_001094573.1  natural resistance-associated macrophage protein 2

      See identical proteins and their annotated locations for NP_001094573.1

      Status: PROVISIONAL

      Source sequence(s)
      BC151587
      UniProtKB/TrEMBL
      A7MBI9, F1N4Z6
      Related
      ENSBTAP00070050518.1, ENSBTAT00070083695.1
      Conserved Domains (2) summary
      TIGR01197
      Location:69 → 468
      nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters
      pfam01566
      Location:91 → 475
      Nramp; Natural resistance-associated macrophage protein

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      28722064..28757980
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024991782.2 → XP_024847550.1  natural resistance-associated macrophage protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1LS52, F1N4Z6
      Conserved Domains (1) summary
      TIGR01197
      Location:96 → 495
      nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

    2. XM_024991780.2 → XP_024847548.1  natural resistance-associated macrophage protein 2 isoform X1

      UniProtKB/TrEMBL
      F1N4Z6
      Related
      ENSBTAP00070050521.1, ENSBTAT00070083698.1
      Conserved Domains (1) summary
      TIGR01197
      Location:69 → 468
      nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

    3. XM_059886456.1 → XP_059742439.1  natural resistance-associated macrophage protein 2 isoform X5

      UniProtKB/TrEMBL
      F1N4Z6

    4. XM_059886455.1 → XP_059742438.1  natural resistance-associated macrophage protein 2 isoform X4

      UniProtKB/TrEMBL
      F1N4Z6

    5. XM_024991781.2 → XP_024847549.1  natural resistance-associated macrophage protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MRJ4, F1N4Z6
      Related
      ENSBTAP00070050519.1, ENSBTAT00070083696.1
      Conserved Domains (1) summary
      TIGR01197
      Location:68 → 467
      nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

    6. XM_059886454.1 → XP_059742437.1  natural resistance-associated macrophage protein 2 isoform X1

      UniProtKB/TrEMBL
      F1N4Z6

    7. XM_024991784.2 → XP_024847552.1  natural resistance-associated macrophage protein 2 isoform X1

      UniProtKB/TrEMBL
      F1N4Z6
      Conserved Domains (1) summary
      TIGR01197
      Location:69 → 468
      nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

    8. XM_024991786.2 → XP_024847554.1  natural resistance-associated macrophage protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MRJ4, F1N4Z6
      Conserved Domains (1) summary
      TIGR01197
      Location:68 → 467
      nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

    9. XM_024991783.2 → XP_024847551.1  natural resistance-associated macrophage protein 2 isoform X1

      UniProtKB/TrEMBL
      F1N4Z6
      Conserved Domains (1) summary
      TIGR01197
      Location:69 → 468
      nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

    10. XM_024991785.2 → XP_024847553.1  natural resistance-associated macrophage protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MRJ4, F1N4Z6
      Conserved Domains (1) summary
      TIGR01197
      Location:68 → 467
      nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters
    Nucleotide Protein Strain
    Heading Accession and Version

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