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    CUX1 cut like homeobox 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 523683, updated on 1-Jan-2025

    Summary

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    Official Symbol
    CUX1provided by VGNC
    Official Full Name
    cut like homeobox 1provided by VGNC
    Primary source
    VGNC:VGNC:27839
    See related
    BGD:BT17046; Ensembl:ENSBTAG00000010659
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    CUTL1
    Orthologs
    human mouse all
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    Genomic context

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    See CUX1 in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (34703181..35052601, complement)

    Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112444377 Neighboring gene SH2B adaptor protein 2 Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene microRNA mir-2388 Neighboring gene uncharacterized LOC132343871 Neighboring gene uncharacterized LOC112444338

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. The small GTPase RAB28 is required for phagocytosis of cone outer segments by the murine retinal pigmented epithelium. Ying G, et al. J Biol Chem, 2018 Nov 9. PMID 30228185, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intra-Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    homeobox protein cut-like 1; protein CASP
    Names
    cut-like 1, CCAAT displacement protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      34703181..35052601 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024985277.2 → XP_024841045.1  protein CASP isoform X10

      UniProtKB/TrEMBL
      Q2HJD6
      Related
      ENSBTAP00000060651.2, ENSBTAT00000087199.2
      Conserved Domains (2) summary
      pfam08172
      Location:421 → 625
      CASP_C; CASP C terminal
      cl25732
      Location:111 → 362
      SMC_N; RecF/RecN/SMC N terminal domain

    2. XM_024985276.2 → XP_024841044.1  protein CASP isoform X9

      UniProtKB/TrEMBL
      A0A3Q1M822, Q2HJD6
      Related
      ENSBTAP00000066571.2, ENSBTAT00000071467.2
      Conserved Domains (2) summary
      pfam08172
      Location:423 → 627
      CASP_C; CASP C terminal
      cl25732
      Location:107 → 368
      SMC_N; RecF/RecN/SMC N terminal domain

    3. XM_024985274.1 → XP_024841042.1  protein CASP isoform X7

      UniProtKB/TrEMBL
      A0AAA9SJ86, Q2HJD6
      Related
      ENSBTAP00000085397.1, ENSBTAT00000117327.1
      Conserved Domains (3) summary
      pfam08172
      Location:512 → 716
      CASP_C; CASP C terminal
      cl25732
      Location:196 → 457
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26464
      Location:4 → 99
      Atrophin-1; Atrophin-1 family

    4. XM_059881599.1 → XP_059737582.1  protein CASP isoform X8

      UniProtKB/TrEMBL
      Q2HJD6

    5. XM_059881598.1 → XP_059737581.1  homeobox protein cut-like 1 isoform X6

    6. XM_024985273.2 → XP_024841041.1  homeobox protein cut-like 1 isoform X5

      UniProtKB/TrEMBL
      F1N693
      Related
      ENSBTAP00000014098.6, ENSBTAT00000014098.7
      Conserved Domains (4) summary
      pfam00046
      Location:1254 → 1307
      Homeobox; Homeobox domain
      pfam02376
      Location:1129 → 1206
      CUT; CUT domain
      cl25732
      Location:13 → 370
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26464
      Location:778 → 940
      Atrophin-1; Atrophin-1 family

    7. XM_024985272.2 → XP_024841040.1  homeobox protein cut-like 1 isoform X3

      Conserved Domains (4) summary
      pfam00046
      Location:1341 → 1394
      Homeobox; Homeobox domain
      pfam02376
      Location:1216 → 1293
      CUT; CUT domain
      cl25732
      Location:129 → 451
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26464
      Location:865 → 1027
      Atrophin-1; Atrophin-1 family

    8. XM_059881597.1 → XP_059737580.1  homeobox protein cut-like 1 isoform X4

    9. XM_059881596.1 → XP_059737579.1  homeobox protein cut-like 1 isoform X2

    10. XM_024985271.2 → XP_024841039.1  homeobox protein cut-like 1 isoform X1

      Conserved Domains (4) summary
      pfam00046
      Location:1343 → 1396
      Homeobox; Homeobox domain
      pfam02376
      Location:1218 → 1295
      CUT; CUT domain
      cl25732
      Location:108 → 459
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26464
      Location:867 → 1029
      Atrophin-1; Atrophin-1 family
    Nucleotide Protein Strain
    Heading Accession and Version

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