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    FLOT2 flotillin 2 [ Gallus gallus (chicken) ]

    Gene ID: 417579, updated on 3-Dec-2024

    Summary

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    Symbol
    FLOT2provided by CGNC
    Full Name
    flotillin 2provided by CGNC
    Primary source
    CGNC:50553
    See related
    Ensembl:ENSGALG00010030004
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    flotillin-2
    Orthologs
    human mouse all
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    Genomic context

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    See FLOT2 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 19 NC_052550.1 (6349971..6363772, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 19 NC_052591.1 (6087015..6100817, complement)

    Chromosome 19 - NC_052550.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121107271 Neighboring gene microRNA 451b Neighboring gene microRNA 144 Neighboring gene dehydrogenase/reductase 13 Neighboring gene PHD finger protein 12

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in protein localization to plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of myoblast differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    flotillin-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001030719.2 → NP_001025890.1  flotillin-2 isoform 1

      See identical proteins and their annotated locations for NP_001025890.1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000323
      UniProtKB/TrEMBL
      A0A8V1AFQ6, F1NFD6, Q5ZHQ3
      Related
      ENSGALP00010044854.1, ENSGALT00010072452.1
      Conserved Domains (3) summary
      cd03399
      Location:18 → 80
      SPFH_flotillin; Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
      pfam15975
      Location:215 → 288
      Flot; Flotillin
      cl19107
      Location:146 → 249
      SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    2. NM_001396723.1 → NP_001383652.1  flotillin-2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000323
      UniProtKB/TrEMBL
      A0A8V1AFR1
      Conserved Domains (2) summary
      COG2268
      Location:6 → 417
      YqiK; Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]
      cd03399
      Location:34 → 178
      SPFH_flotillin; Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    3. NM_001396724.1 → NP_001383653.1  flotillin-2 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000323
      UniProtKB/TrEMBL
      A0A1D5PCD1, A0A8V1AFR1
      Related
      ENSGALP00010044859.1, ENSGALT00010072458.1
      Conserved Domains (2) summary
      COG2268
      Location:6 → 417
      YqiK; Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]
      cd03399
      Location:34 → 178
      SPFH_flotillin; Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    4. NM_001396725.1 → NP_001383654.1  flotillin-2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000323
      UniProtKB/TrEMBL
      A0A8V1AFR1, A0A8V1AP24
      Related
      ENSGALP00010044856.1, ENSGALT00010072454.1
      Conserved Domains (2) summary
      COG2268
      Location:18 → 407
      YqiK; Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]
      cd03399
      Location:24 → 168
      SPFH_flotillin; Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052550.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      6349971..6363772 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046902389.1 → XP_046758345.1  flotillin-2 isoform X5

      UniProtKB/TrEMBL
      A0A8V1AL42
      Related
      ENSGALP00010044858.1, ENSGALT00010072456.1

    2. XM_040650080.2 → XP_040506014.1  flotillin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V1AFR1
      Related
      ENSGALP00010044857.1, ENSGALT00010072455.1
      Conserved Domains (2) summary
      COG2268
      Location:6 → 440
      YqiK; Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]
      cd03399
      Location:34 → 201
      SPFH_flotillin; Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    3. XM_046902391.1 → XP_046758347.1  flotillin-2 isoform X5

      UniProtKB/TrEMBL
      A0A8V1AL42

    4. XM_040650081.2 → XP_040506015.1  flotillin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8V1AFR1
      Conserved Domains (2) summary
      COG2268
      Location:58 → 430
      YqiK; Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]
      cd03399
      Location:24 → 191
      SPFH_flotillin; Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    5. XM_046902387.1 → XP_046758343.1  flotillin-2 isoform X3

      UniProtKB/TrEMBL
      A0A8V1AL42

    6. XM_046902390.1 → XP_046758346.1  flotillin-2 isoform X5

      UniProtKB/TrEMBL
      A0A8V1AL42
      Related
      ENSGALP00010044855.1, ENSGALT00010072453.1

    7. XM_046902388.1 → XP_046758344.1  flotillin-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V1AL42

    8. XM_015295767.3 → XP_015151253.1  flotillin-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V1AL42
      Conserved Domains (4) summary
      smart00244
      Location:38 → 216
      PHB; prohibitin homologues
      cd03399
      Location:1 → 129
      SPFH_flotillin; Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
      pfam15975
      Location:264 → 337
      Flot; Flotillin
      cl19107
      Location:195 → 298
      SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052591.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      6087015..6100817 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046930108.1 → XP_046786064.1  flotillin-2 isoform X5

      UniProtKB/TrEMBL
      A0A8V1AL42

    2. XM_046930103.1 → XP_046786059.1  flotillin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V1AFR1

    3. XM_046930110.1 → XP_046786066.1  flotillin-2 isoform X5

      UniProtKB/TrEMBL
      A0A8V1AL42

    4. XM_046930104.1 → XP_046786060.1  flotillin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8V1AFR1

    5. XM_046930105.1 → XP_046786061.1  flotillin-2 isoform X3

      UniProtKB/TrEMBL
      A0A8V1AL42

    6. XM_046930109.1 → XP_046786065.1  flotillin-2 isoform X5

      UniProtKB/TrEMBL
      A0A8V1AL42

    7. XM_046930106.1 → XP_046786062.1  flotillin-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V1AL42

    8. XM_046930107.1 → XP_046786063.1  flotillin-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V1AL42
    Nucleotide Protein Strain
    Heading Accession and Version

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