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    LRRC8A leucine rich repeat containing 8 VRAC subunit A [ Gallus gallus (chicken) ]

    Gene ID: 417201, updated on 3-Dec-2024

    Summary

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    Symbol
    LRRC8Aprovided by CGNC
    Full Name
    leucine rich repeat containing 8 VRAC subunit Aprovided by CGNC
    Primary source
    CGNC:3381
    See related
    Ensembl:ENSGALG00010028584
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    LRRC8
    Orthologs
    human mouse all
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    Genomic context

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    See LRRC8A in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 17 NC_052548.1 (5970680..5991949)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 17 NC_052589.1 (5384817..5406092)

    Chromosome 17 - NC_052548.1Genomic Context describing neighboring genes Neighboring gene endonuclease G Neighboring gene SPOUT domain containing methyltransferase 1 Neighboring gene kynurenine aminotransferase 1 Neighboring gene phytanoyl-CoA dioxygenase domain containing 1 Neighboring gene dolichol kinase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    volume-regulated anion channel subunit LRRC8A
    Names
    leucine rich repeat containing 8 family member A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052548.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      5970680..5991949
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015279568.4 → XP_015135054.1  volume-regulated anion channel subunit LRRC8A

      UniProtKB/TrEMBL
      A0A1D5NV54, A0A8V1AJE6, E1BQK4
      Conserved Domains (3) summary
      COG4886
      Location:552 → 780
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:546 → 568
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12534
      Location:1 → 340
      Pannexin_like; Pannexin-like TM region of LRRC8

    2. XM_015279567.4 → XP_015135053.1  volume-regulated anion channel subunit LRRC8A

      UniProtKB/TrEMBL
      A0A1D5NV54, A0A8V1AJE6, E1BQK4
      Conserved Domains (3) summary
      COG4886
      Location:552 → 780
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:546 → 568
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12534
      Location:1 → 340
      Pannexin_like; Pannexin-like TM region of LRRC8

    3. XM_003642283.6 → XP_003642331.1  volume-regulated anion channel subunit LRRC8A

      See identical proteins and their annotated locations for XP_003642331.1

      UniProtKB/TrEMBL
      A0A1D5NV54, A0A8V1AJE6, E1BQK4
      Related
      ENSGALP00010042663.1, ENSGALT00010069221.1
      Conserved Domains (3) summary
      COG4886
      Location:552 → 780
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:546 → 568
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12534
      Location:1 → 340
      Pannexin_like; Pannexin-like TM region of LRRC8

    4. XM_046901893.1 → XP_046757849.1  volume-regulated anion channel subunit LRRC8A

      UniProtKB/TrEMBL
      A0A1D5NV54, A0A8V1AJE6, E1BQK4

    5. XM_040649297.2 → XP_040505231.1  volume-regulated anion channel subunit LRRC8A

      UniProtKB/TrEMBL
      A0A1D5NV54, A0A8V1AJE6, E1BQK4
      Conserved Domains (3) summary
      COG4886
      Location:552 → 780
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:546 → 568
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12534
      Location:1 → 340
      Pannexin_like; Pannexin-like TM region of LRRC8

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052589.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      5384817..5406092
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040685901.2 → XP_040541835.1  volume-regulated anion channel subunit LRRC8A

      UniProtKB/TrEMBL
      A0A1D5NV54, A0A8V1AJE6, E1BQK4
      Conserved Domains (3) summary
      COG4886
      Location:552 → 780
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:546 → 568
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12534
      Location:1 → 340
      Pannexin_like; Pannexin-like TM region of LRRC8

    2. XM_040685900.2 → XP_040541834.1  volume-regulated anion channel subunit LRRC8A

      UniProtKB/TrEMBL
      A0A1D5NV54, A0A8V1AJE6, E1BQK4
      Conserved Domains (3) summary
      COG4886
      Location:552 → 780
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:546 → 568
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12534
      Location:1 → 340
      Pannexin_like; Pannexin-like TM region of LRRC8

    3. XM_040685899.2 → XP_040541833.1  volume-regulated anion channel subunit LRRC8A

      UniProtKB/TrEMBL
      A0A1D5NV54, A0A8V1AJE6, E1BQK4
      Conserved Domains (3) summary
      COG4886
      Location:552 → 780
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:546 → 568
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12534
      Location:1 → 340
      Pannexin_like; Pannexin-like TM region of LRRC8

    4. XM_046929202.1 → XP_046785158.1  volume-regulated anion channel subunit LRRC8A

      UniProtKB/TrEMBL
      A0A1D5NV54, A0A8V1AJE6, E1BQK4

    5. XM_040685902.2 → XP_040541836.1  volume-regulated anion channel subunit LRRC8A

      UniProtKB/TrEMBL
      A0A1D5NV54, A0A8V1AJE6, E1BQK4
      Conserved Domains (3) summary
      COG4886
      Location:552 → 780
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:546 → 568
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12534
      Location:1 → 340
      Pannexin_like; Pannexin-like TM region of LRRC8
    Nucleotide Protein Strain
    Heading Accession and Version

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