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    WNK1 WNK lysine deficient protein kinase 1 [ Gallus gallus (chicken) ]

    Gene ID: 427925, updated on 17-Aug-2024

    Summary

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    Symbol
    WNK1provided by CGNC
    Full Name
    WNK lysine deficient protein kinase 1provided by CGNC
    Primary source
    CGNC:9833
    See related
    Ensembl:ENSGALG00010012339
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See WNK1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (60491015..60589727)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (60812255..60911010)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene ninjurin 2 Neighboring gene uncharacterized LOC124417239 Neighboring gene uncharacterized LOC121107292 Neighboring gene RAD52 homolog, DNA repair protein Neighboring gene uncharacterized LOC121107293 Neighboring gene ELKS/RAB6-interacting/CAST family member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables chloride channel inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables potassium channel inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in monoatomic ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of potassium ion import across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of sodium ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase WNK1
    XP_015142178.2
    XP_015142181.2
    XP_015142190.2
    XP_015142201.2
    XP_015142207.2
    XP_015142215.2
    XP_015142223.2
    XP_015142230.2
    XP_015142237.2
    XP_040506510.1
    XP_040506528.1
    XP_040506546.1
    XP_040506553.1
    XP_040515159.1
    XP_040515160.1
    XP_040515161.1
    XP_040515162.1
    XP_040515163.1
    XP_040515164.1
    XP_040515165.1
    XP_040515166.1
    XP_040515167.1
    XP_040515168.1
    XP_040515170.1
    XP_040515171.1
    XP_040515172.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      60491015..60589727
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040650576.2 → XP_040506510.1  serine/threonine-protein kinase WNK1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YE30
      Conserved Domains (1) summary
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    2. XM_015286692.4 → XP_015142178.2  serine/threonine-protein kinase WNK1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YE30
      Conserved Domains (1) summary
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    3. XM_015286704.4 → XP_015142190.2  serine/threonine-protein kinase WNK1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0YE30
      Conserved Domains (1) summary
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    4. XM_015286721.4 → XP_015142207.2  serine/threonine-protein kinase WNK1 isoform X6

      UniProtKB/TrEMBL
      A0A8V0YE30
      Related
      ENSGALP00010017174.1, ENSGALT00010029543.1
      Conserved Domains (1) summary
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    5. XM_015286715.4 → XP_015142201.2  serine/threonine-protein kinase WNK1 isoform X5

      UniProtKB/TrEMBL
      A0A8V0YE30
      Conserved Domains (2) summary
      PHA03247
      Location:1577 → 1880
      PHA03247; large tegument protein UL36; Provisional
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    6. XM_040650594.2 → XP_040506528.1  serine/threonine-protein kinase WNK1 isoform X7

      UniProtKB/TrEMBL
      A0A8V0YE30
      Conserved Domains (2) summary
      PHA03247
      Location:1577 → 1880
      PHA03247; large tegument protein UL36; Provisional
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    7. XM_015286695.4 → XP_015142181.2  serine/threonine-protein kinase WNK1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YF83
      Conserved Domains (1) summary
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    8. XM_015286737.4 → XP_015142223.2  serine/threonine-protein kinase WNK1 isoform X9

      UniProtKB/TrEMBL
      A0A8V0YE18
      Conserved Domains (1) summary
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    9. XM_040650612.2 → XP_040506546.1  serine/threonine-protein kinase WNK1 isoform X10

      UniProtKB/TrEMBL
      A0A8V0YE18
      Related
      ENSGALP00010017177.1, ENSGALT00010029550.1
      Conserved Domains (1) summary
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    10. XM_015286729.4 → XP_015142215.2  serine/threonine-protein kinase WNK1 isoform X8

      UniProtKB/TrEMBL
      A0A8V0YE30
      Conserved Domains (2) summary
      PHA03247
      Location:716 → 1248
      PHA03247; large tegument protein UL36; Provisional
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    11. XM_015286744.4 → XP_015142230.2  serine/threonine-protein kinase WNK1 isoform X11

      UniProtKB/TrEMBL
      A0A8V0YE30
      Related
      ENSGALP00010017187.1, ENSGALT00010029560.1
      Conserved Domains (2) summary
      PHA03247
      Location:785 → 1105
      PHA03247; large tegument protein UL36; Provisional
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    12. XM_015286751.4 → XP_015142237.2  serine/threonine-protein kinase WNK1 isoform X12

      UniProtKB/TrEMBL
      A0A8V0YE30
      Conserved Domains (1) summary
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    13. XM_040650619.2 → XP_040506553.1  serine/threonine-protein kinase WNK1 isoform X13

      UniProtKB/TrEMBL
      A0A8V0YM64
      Conserved Domains (1) summary
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      60812255..60911010
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040659226.2 → XP_040515160.1  serine/threonine-protein kinase WNK1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YE30
      Conserved Domains (1) summary
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    2. XM_040659225.2 → XP_040515159.1  serine/threonine-protein kinase WNK1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YE30
      Conserved Domains (1) summary
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    3. XM_040659228.2 → XP_040515162.1  serine/threonine-protein kinase WNK1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0YE30
      Conserved Domains (1) summary
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    4. XM_040659230.2 → XP_040515164.1  serine/threonine-protein kinase WNK1 isoform X6

      UniProtKB/TrEMBL
      A0A8V0YE30
      Conserved Domains (1) summary
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    5. XM_040659229.2 → XP_040515163.1  serine/threonine-protein kinase WNK1 isoform X5

      UniProtKB/TrEMBL
      A0A8V0YE30
      Conserved Domains (2) summary
      PHA03247
      Location:1577 → 1880
      PHA03247; large tegument protein UL36; Provisional
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    6. XM_040659231.2 → XP_040515165.1  serine/threonine-protein kinase WNK1 isoform X7

      UniProtKB/TrEMBL
      A0A8V0YE30
      Conserved Domains (2) summary
      PHA03247
      Location:1577 → 1880
      PHA03247; large tegument protein UL36; Provisional
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    7. XM_040659227.2 → XP_040515161.1  serine/threonine-protein kinase WNK1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YF83
      Conserved Domains (1) summary
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    8. XM_040659233.2 → XP_040515167.1  serine/threonine-protein kinase WNK1 isoform X9

      UniProtKB/TrEMBL
      A0A8V0YE18
      Conserved Domains (1) summary
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    9. XM_040659234.2 → XP_040515168.1  serine/threonine-protein kinase WNK1 isoform X10

      UniProtKB/TrEMBL
      A0A8V0YE18
      Conserved Domains (1) summary
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    10. XM_040659232.2 → XP_040515166.1  serine/threonine-protein kinase WNK1 isoform X8

      UniProtKB/TrEMBL
      A0A8V0YE30
      Conserved Domains (2) summary
      PHA03247
      Location:716 → 1248
      PHA03247; large tegument protein UL36; Provisional
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    11. XM_040659236.2 → XP_040515170.1  serine/threonine-protein kinase WNK1 isoform X11

      UniProtKB/TrEMBL
      A0A8V0YE30
      Conserved Domains (2) summary
      PHA03247
      Location:785 → 1105
      PHA03247; large tegument protein UL36; Provisional
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    12. XM_040659237.2 → XP_040515171.1  serine/threonine-protein kinase WNK1 isoform X12

      UniProtKB/TrEMBL
      A0A8V0YE30
      Conserved Domains (1) summary
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1

    13. XM_040659238.2 → XP_040515172.1  serine/threonine-protein kinase WNK1 isoform X13

      UniProtKB/TrEMBL
      A0A8V0YM64
      Conserved Domains (1) summary
      cd14030
      Location:200 → 488
      STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
    Nucleotide Protein Strain
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