NUDT7 nudix hydrolase 7 [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: NUDT7provided by CGNC
Official Full Name: nudix hydrolase 7provided by CGNC
Primary source: CGNC:50084
See related: Ensembl:ENSGALG00010007765
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	11	NC_052542.1 (13604132..13607134)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	11	NC_052583.1 (13951810..13954823)

Chromosome 11 - NC_052542.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables acetyl-CoA hydrolase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables coenzyme A diphosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables magnesium ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables manganese ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in coenzyme A catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in nucleoside diphosphate metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: peroxisomal coenzyme A diphosphatase NUDT7

Names: nudix (nucleoside diphosphate linked moiety X)-type motif 7

NP_001238995.3

EC 3.6.1.-

EC 3.6.1.77

XP_015147995.3

EC 3.6.1.-

EC 3.6.1.77

XP_046781521.1

EC 3.6.1.-

EC 3.6.1.77

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001252066.3 → NP_001238995.3 peroxisomal coenzyme A diphosphatase NUDT7

Status: VALIDATED

Description

Transcript Variant: This variant (1) represents the longer transcript and encodes the functional protein.

Source sequence(s)

JAENSK010000248

UniProtKB/TrEMBL

A0A8V0Y1Q3

Related

ENSGALP00010010104.1, ENSGALT00010018454.1

Conserved Domains (1) summary

cd03426
Location:38 → 199

CoAse; Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative ...

RNA

NR_073539.4 RNA Sequence

Status: VALIDATED

Description

Transcript Variant: This variant (2) lacks an alternate 5 exon compared to variant 1. This variant is represented as non-coding because the use of the 5_-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

JAENSK010000248

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052542.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

13604132..13607134

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015292509.4 → XP_015147995.3 peroxisomal coenzyme A diphosphatase NUDT7 isoform X1

Conserved Domains (1) summary

cd03426
Location:103 → 264

CoAse; Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative ...