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    DDX3X DEAD-box helicase 3X [ Gallus gallus (chicken) ]

    Gene ID: 418567, updated on 3-Dec-2024

    Summary

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    Official Symbol
    DDX3Xprovided by CGNC
    Official Full Name
    DEAD-box helicase 3Xprovided by CGNC
    Primary source
    CGNC:50794
    See related
    Ensembl:ENSGALG00010002476
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    CPL10
    Orthologs
    human mouse all
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    Genomic context

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    See DDX3X in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (112120026..112137466, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (112174183..112191623, complement)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene calcium/calmodulin dependent serine protein kinase Neighboring gene G protein-coupled receptor 34 Neighboring gene uncharacterized LOC121109949 Neighboring gene nyctalopin Neighboring gene uncharacterized LOC101750611 Neighboring gene ribosomal protein L8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Chicken DDX3X Activates IFN-β via the chSTING-chIRF7-IFN-β Signaling Axis. Niu Q, et al. Front Immunol, 2019. PMID 31057547, Free PMC Article
    2. Male-biased miR-92 from early chicken embryonic gonads directly targets ATRX and DDX3X. Miao N, et al. Gene, 2017 Aug 30. PMID 28554548
    3. Isolation of chicken vasa homolog gene and tracing the origin of primordial germ cells. Tsunekawa N, et al. Development, 2000 Jun. PMID 10821771
    4. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in gamete generation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in P granule IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ATP-dependent RNA helicase DDX3X
    Names
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked
    DEAD-box helicase 3, X-linked
    NP_001025971.1
    XP_015157021.1
    XP_046763877.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001030800.2 → NP_001025971.1  ATP-dependent RNA helicase DDX3X

      See identical proteins and their annotated locations for NP_001025971.1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000021
      UniProtKB/TrEMBL
      A0A3Q2U0S7, F1NIX2, Q5F491
      Related
      ENSGALP00010003567.1, ENSGALT00010005736.1
      Conserved Domains (1) summary
      COG0513
      Location:148 → 583
      SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      112120026..112137466 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015301535.4 → XP_015157021.1  ATP-dependent RNA helicase DDX3X isoform X1

      UniProtKB/TrEMBL
      A0A3Q2U0S7, A0A8V0XGV3
      Related
      ENSGALP00010003563.1, ENSGALT00010005730.1
      Conserved Domains (3) summary
      cd00268
      Location:174 → 396
      DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
      PTZ00110
      Location:55 → 583
      PTZ00110; helicase; Provisional
      pfam00271
      Location:418 → 528
      Helicase_C; Helicase conserved C-terminal domain

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      112174183..112191623 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046907921.1 → XP_046763877.1  ATP-dependent RNA helicase DDX3X isoform X1

      UniProtKB/TrEMBL
      A0A3Q2U0S7, A0A8V0XGV3
    Nucleotide Protein Strain
    Heading Accession and Version

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