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    SH3GL1 SH3 domain containing GRB2 like 1, endophilin A2 [ Gallus gallus (chicken) ]

    Gene ID: 395202, updated on 3-Dec-2024

    Summary

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    Symbol
    SH3GL1provided by CGNC
    Full Name
    SH3 domain containing GRB2 like 1, endophilin A2provided by CGNC
    Primary source
    CGNC:49210
    See related
    Ensembl:ENSGALG00010027192
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    SH3P8
    Orthologs
    human mouse all
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    Genomic context

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    See SH3GL1 in Genome Data Viewer
    Location:
    chromosome: 28
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 28 NC_052559.1 (2914322..2940969, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 28 NC_052600.1 (2480362..2507017, complement)

    Chromosome 28 - NC_052559.1Genomic Context describing neighboring genes Neighboring gene mex-3 RNA binding family member D Neighboring gene MIER family member 2 Neighboring gene chromatin assembly factor 1 subunit A Neighboring gene UBX domain protein 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Receptor-mediated chicken oocyte growth: differential expression of endophilin isoforms in developing follicles. Hirayama S, et al. Biol Reprod, 2003 May. PMID 12606338
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in synaptic vesicle uncoating IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in glutamatergic synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in presynapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    endophilin-A2
    Names
    SH3 domain-containing GRB2-like protein 2
    SH3-domain GRB2-like 1
    endophilin II
    endophilin-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_204529.2 → NP_989860.1  endophilin-A2

      See identical proteins and their annotated locations for NP_989860.1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000375
      UniProtKB/Swiss-Prot
      Q8AXV0
      UniProtKB/TrEMBL
      A0A8V1AAE6
      Related
      ENSGALP00010040194.1, ENSGALT00010065928.1
      Conserved Domains (2) summary
      cd07614
      Location:25 → 247
      BAR_Endophilin_A2; The Bin/Amphiphysin/Rvs (BAR) domain of Endophilin-A2
      cd11803
      Location:308 → 362
      SH3_Endophilin_A; Src homology 3 domain of Endophilin-A

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052559.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      2914322..2940969 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015299915.4 → XP_015155401.2  endophilin-A2 isoform X2

      UniProtKB/TrEMBL
      A0A8V1A7T9
      Related
      ENSGALP00010040197.1, ENSGALT00010065931.1
      Conserved Domains (2) summary
      cd07614
      Location:25 → 247
      BAR_Endophilin_A2; The Bin/Amphiphysin/Rvs (BAR) domain of Endophilin-A2
      cd11803
      Location:290 → 344
      SH3_Endophilin_A; Src homology 3 domain of Endophilin-A

    2. XM_046904526.1 → XP_046760482.1  endophilin-A2 isoform X4

      UniProtKB/TrEMBL
      A0A8V1AAE6

    3. XM_015299917.3 → XP_015155403.2  endophilin-A2 isoform X3

      UniProtKB/TrEMBL
      A0A8V1A7T9
      Conserved Domains (2) summary
      cd11803
      Location:279 → 333
      SH3_Endophilin_A; Src homology 3 domain of Endophilin-A
      cl12013
      Location:14 → 236
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    4. XM_015299916.4 → XP_015155402.2  endophilin-A2 isoform X1

      UniProtKB/TrEMBL
      A0A8V1AAE6
      Conserved Domains (2) summary
      cd07614
      Location:14 → 236
      BAR_Endophilin_A2; The Bin/Amphiphysin/Rvs (BAR) domain of Endophilin-A2
      cd11803
      Location:297 → 351
      SH3_Endophilin_A; Src homology 3 domain of Endophilin-A

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052600.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      2480362..2507017 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046933670.1 → XP_046789626.1  endophilin-A2 isoform X2

      UniProtKB/TrEMBL
      A0A8V1A7T9

    2. XM_046933669.1 → XP_046789625.1  endophilin-A2 isoform X6

      UniProtKB/TrEMBL
      A0A8V1A7T9

    3. XM_046933668.1 → XP_046789624.1  endophilin-A2 isoform X5

      UniProtKB/TrEMBL
      A0A8V1AAE6
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8AXV0.1 GenPept UniProtKB/Swiss-Prot:Q8AXV0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials