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    RPS6KA5 ribosomal protein S6 kinase A5 [ Gallus gallus (chicken) ]

    Gene ID: 423408, updated on 17-Aug-2024

    Summary

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    Symbol
    RPS6KA5provided by CGNC
    Full Name
    ribosomal protein S6 kinase A5provided by CGNC
    Primary source
    CGNC:51959
    See related
    Ensembl:ENSGALG00010017703
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See RPS6KA5 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (43629286..43762652, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (43598030..43731435, complement)

    Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107053531 Neighboring gene uncharacterized LOC107053532 Neighboring gene tetratricopeptide repeat domain 7B Neighboring gene C14orf159 homolog Neighboring gene G protein-coupled receptor 4 Neighboring gene coiled-coil domain containing 88B Neighboring gene protein phosphatase 4 regulatory subunit 3A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ribosomal protein S6 kinase alpha-5
    Names
    S6K-alpha-5
    ribosomal protein S6 kinase, 90kDa, polypeptide 5
    ribosomal protein S6 kinase, polypeptide 5
    NP_001012605.1
    XP_025006548.1
    XP_040556975.1
    XP_046774567.1
    XP_046774568.1
    XP_046774569.1
    XP_046774570.1
    XP_046774571.1
    XP_046774572.1
    XP_046797741.1
    XP_046797742.1
    XP_046797743.1
    XP_046797744.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012587.3 → NP_001012605.1  ribosomal protein S6 kinase alpha-5

      See identical proteins and their annotated locations for NP_001012605.1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000215
      UniProtKB/Swiss-Prot
      Q5F3L1
      Related
      ENSGALP00010025288.1, ENSGALT00010042798.1
      Conserved Domains (4) summary
      smart00133
      Location:310 → 369
      S_TK_X; Extension to Ser/Thr-type protein kinases
      smart00220
      Location:39 → 308
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05613
      Location:38 → 327
      STKc_MSK1_N; N-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
      cd14179
      Location:408 → 717
      STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      43629286..43762652 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046941787.1 → XP_046797743.1  ribosomal protein S6 kinase alpha-5 isoform X2

    2. XM_046941785.1 → XP_046797741.1  ribosomal protein S6 kinase alpha-5 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YW25
      Related
      ENSGALP00010025285.1, ENSGALT00010042795.1

    3. XM_046941786.1 → XP_046797742.1  ribosomal protein S6 kinase alpha-5 isoform X2

    4. XM_040701041.2 → XP_040556975.1  ribosomal protein S6 kinase alpha-5 isoform X4

      Conserved Domains (2) summary
      cd14179
      Location:233 → 542
      STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
      cl21453
      Location:17 → 195
      PKc_like; Protein Kinases, catalytic domain

    5. XM_025150780.3 → XP_025006548.1  ribosomal protein S6 kinase alpha-5 isoform X3

      Conserved Domains (2) summary
      cd14179
      Location:243 → 552
      STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
      cl21453
      Location:28 → 205
      PKc_like; Protein Kinases, catalytic domain

    6. XM_046941788.1 → XP_046797744.1  ribosomal protein S6 kinase alpha-5 isoform X5

    RNA

    1. XR_005860048.2 RNA Sequence

    2. XR_005860047.2 RNA Sequence

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      43598030..43731435 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046918613.1 → XP_046774569.1  ribosomal protein S6 kinase alpha-5 isoform X2

    2. XM_046918611.1 → XP_046774567.1  ribosomal protein S6 kinase alpha-5 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YW25

    3. XM_046918612.1 → XP_046774568.1  ribosomal protein S6 kinase alpha-5 isoform X2

    4. XM_046918615.1 → XP_046774571.1  ribosomal protein S6 kinase alpha-5 isoform X4

      Conserved Domains (2) summary
      cd14179
      Location:233 → 542
      STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
      cl21453
      Location:17 → 195
      PKc_like; Protein Kinases, catalytic domain

    5. XM_046918614.1 → XP_046774570.1  ribosomal protein S6 kinase alpha-5 isoform X3

    6. XM_046918616.1 → XP_046774572.1  ribosomal protein S6 kinase alpha-5 isoform X5

    RNA

    1. XR_006934711.1 RNA Sequence

    2. XR_006934710.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5F3L1.1 GenPept UniProtKB/Swiss-Prot:Q5F3L1

    Gene LinkOut

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