ZIC1 Zic family member 1 [Gallus gallus (chicken)] - Gene

Summary

Symbol: ZIC1provided by CGNC
Full Name: Zic family member 1provided by CGNC
Primary source: CGNC:49043
See related: Ensembl:ENSGALG00010017016
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	9	NC_052540.1 (11601968..11607494)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	9	NC_052581.1 (11404692..11409419)

Chromosome 9 - NC_052540.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

MYC, TERT, and ZIC1 genes are common targets of viral integration.
Title: The MYC, TERT, and ZIC1 genes are common targets of viral integration and transcriptional deregulation in avian leukosis virus subgroup J-induced myeloid leukosis.
Data have identified a novel chick gene and show it has a role in the correct specification of Zic-1 at the neural plate border.
Title: ILF-3 is a regulator of the neural plate border marker Zic1 in chick embryos.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in central nervous system development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: zinc finger protein ZIC 1

Names: Zic family member 1 (odd-paired homolog, Drosophila); zinc finger protein Zic1; zinc finger protein of the cerebellum 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_204254.2 → NP_989585.2 zinc finger protein ZIC 1

Status: VALIDATED

Source sequence(s)

JAENSK010000240

UniProtKB/Swiss-Prot

Q8JJC0

UniProtKB/TrEMBL

A0A1D5PND2

Related

ENSGALP00010024046.1, ENSGALT00010041098.1

Conserved Domains (3) summary

COG5189
Location:295 → 379

SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]

sd00017
Location:273 → 293

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam18366
Location:216 → 261

zf_ZIC; Zic proteins zinc finger domain