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    EPN2 epsin 2 [ Gallus gallus (chicken) ]

    Gene ID: 416524, updated on 3-Dec-2024

    Summary

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    Symbol
    EPN2provided by CGNC
    Full Name
    epsin 2provided by CGNC
    Primary source
    CGNC:66261
    See related
    Ensembl:ENSGALG00010017407
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    epsin-2
    Orthologs
    human mouse all
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    Genomic context

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    See EPN2 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 14 NC_052545.1 (5183199..5228187)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 14 NC_052586.1 (5178242..5223254)

    Chromosome 14 - NC_052545.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 5 member 10 Neighboring gene family with sequence similarity 83, member G Neighboring gene GRB2 related adaptor protein like Neighboring gene microRNA 1551 Neighboring gene uncharacterized LOC107054611 Neighboring gene B9 domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptome analysis for the chicken based on 19,626 finished cDNA sequences and 485,337 expressed sequence tags. Hubbard SJ, et al. Genome Res, 2005 Jan. PMID 15590942, Free PMC Article
    2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables clathrin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of clathrin vesicle coat IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    epsin-2

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012788.1 → NP_001012806.1  epsin-2

      See identical proteins and their annotated locations for NP_001012806.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ719427
      UniProtKB/TrEMBL
      A0A8V0Z104, Q5ZMF7
      Related
      ENSGALP00010024595.1, ENSGALT00010042017.1
      Conserved Domains (3) summary
      COG3334
      Location:184 → 286
      MotE; Flagellar motility protein MotE, a chaperone for MotC folding [Cell motility]
      cd03571
      Location:19 → 141
      ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...
      cl21487
      Location:263 → 399
      OM_channels; Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in strand and shear number. Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20) ...

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052545.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      5183199..5228187
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015294185.4 → XP_015149671.1  epsin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YU62
      Conserved Domains (2) summary
      PHA03247
      Location:287 → 555
      PHA03247; large tegument protein UL36; Provisional
      cd16990
      Location:19 → 141
      ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

    2. XM_025155087.3 → XP_025010855.1  epsin-2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q2UI02, A0A8V0YU62
      Conserved Domains (3) summary
      COG3334
      Location:184 → 286
      MotE; Flagellar motility protein MotE, a chaperone for MotC folding [Cell motility]
      cd03571
      Location:19 → 141
      ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...
      cl26464
      Location:283 → 551
      Atrophin-1; Atrophin-1 family

    3. XM_025155090.3 → XP_025010858.1  epsin-2 isoform X5

      UniProtKB/TrEMBL
      A0A3Q3B230, A0A8V0Z104
      Conserved Domains (2) summary
      cd16990
      Location:19 → 141
      ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family
      NF033761
      Location:275 → 450
      gliding_GltJ; adventurous gliding motility protein GltJ

    4. XM_025155088.3 → XP_025010856.1  epsin-2 isoform X3

      UniProtKB/TrEMBL
      A0A3Q2U2K2, A0A8V0YU62
      Conserved Domains (2) summary
      cd03571
      Location:19 → 141
      ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...
      cl26464
      Location:252 → 520
      Atrophin-1; Atrophin-1 family

    5. XM_040647370.2 → XP_040503304.1  epsin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YU62
      Conserved Domains (2) summary
      PHA03247
      Location:287 → 555
      PHA03247; large tegument protein UL36; Provisional
      cd16990
      Location:19 → 141
      ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

    6. XM_046900619.1 → XP_046756575.1  epsin-2 isoform X5

      UniProtKB/TrEMBL
      A0A3Q3B230, A0A8V0Z104

    7. XM_015294184.4 → XP_015149670.1  epsin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YU62
      Related
      ENSGALP00010024591.1, ENSGALT00010042012.1
      Conserved Domains (2) summary
      PHA03247
      Location:287 → 555
      PHA03247; large tegument protein UL36; Provisional
      cd16990
      Location:19 → 141
      ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

    8. XM_015294190.4 → XP_015149676.1  epsin-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0Z104
      Conserved Domains (1) summary
      cd03571
      Location:19 → 141
      ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...

    9. XM_015294187.4 → XP_015149673.1  epsin-2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q2UI02, A0A8V0YU62
      Related
      ENSGALP00010024594.1, ENSGALT00010042015.1
      Conserved Domains (3) summary
      COG3334
      Location:184 → 286
      MotE; Flagellar motility protein MotE, a chaperone for MotC folding [Cell motility]
      cd03571
      Location:19 → 141
      ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...
      cl26464
      Location:283 → 551
      Atrophin-1; Atrophin-1 family

    10. XM_040647371.2 → XP_040503305.1  epsin-2 isoform X5

      UniProtKB/TrEMBL
      A0A3Q3B230, A0A8V0Z104
      Conserved Domains (2) summary
      cd16990
      Location:19 → 141
      ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family
      NF033761
      Location:275 → 450
      gliding_GltJ; adventurous gliding motility protein GltJ

    11. XM_015294189.4 → XP_015149675.1  epsin-2 isoform X3

      UniProtKB/TrEMBL
      A0A3Q2U2K2, A0A8V0YU62
      Related
      ENSGALP00010024590.1, ENSGALT00010042010.1
      Conserved Domains (2) summary
      cd03571
      Location:19 → 141
      ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...
      cl26464
      Location:252 → 520
      Atrophin-1; Atrophin-1 family

    12. XM_015294186.4 → XP_015149672.1  epsin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YU62
      Conserved Domains (2) summary
      PHA03247
      Location:287 → 555
      PHA03247; large tegument protein UL36; Provisional
      cd16990
      Location:19 → 141
      ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

    13. XM_040647366.2 → XP_040503300.1  epsin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YU62
      Conserved Domains (2) summary
      PHA03247
      Location:287 → 555
      PHA03247; large tegument protein UL36; Provisional
      cd16990
      Location:19 → 141
      ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

    14. XM_040647368.2 → XP_040503302.1  epsin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YU62
      Conserved Domains (2) summary
      PHA03247
      Location:287 → 555
      PHA03247; large tegument protein UL36; Provisional
      cd16990
      Location:19 → 141
      ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

    15. XM_040647365.2 → XP_040503299.1  epsin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YU62
      Conserved Domains (2) summary
      PHA03247
      Location:287 → 555
      PHA03247; large tegument protein UL36; Provisional
      cd16990
      Location:19 → 141
      ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

    16. XM_046900616.1 → XP_046756572.1  epsin-2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q2UI02, A0A8V0YU62

    17. XM_046900618.1 → XP_046756574.1  epsin-2 isoform X5

      UniProtKB/TrEMBL
      A0A3Q3B230, A0A8V0Z104
      Related
      ENSGALP00010024586.1, ENSGALT00010042005.1

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052586.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      5178242..5223254
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046927379.1 → XP_046783335.1  epsin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YU62

    2. XM_046927386.1 → XP_046783342.1  epsin-2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q2UI02, A0A8V0YU62

    3. XM_046927392.1 → XP_046783348.1  epsin-2 isoform X5

      UniProtKB/TrEMBL
      A0A3Q3B230, A0A8V0Z104

    4. XM_046927389.1 → XP_046783345.1  epsin-2 isoform X3

      UniProtKB/TrEMBL
      A0A3Q2U2K2, A0A8V0YU62

    5. XM_046927384.1 → XP_046783340.1  epsin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YU62

    6. XM_046927394.1 → XP_046783350.1  epsin-2 isoform X5

      UniProtKB/TrEMBL
      A0A3Q3B230, A0A8V0Z104

    7. XM_046927378.1 → XP_046783334.1  epsin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YU62

    8. XM_046927390.1 → XP_046783346.1  epsin-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0Z104

    9. XM_046927385.1 → XP_046783341.1  epsin-2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q2UI02, A0A8V0YU62

    10. XM_046927391.1 → XP_046783347.1  epsin-2 isoform X5

      UniProtKB/TrEMBL
      A0A3Q3B230, A0A8V0Z104

    11. XM_046927388.1 → XP_046783344.1  epsin-2 isoform X3

      UniProtKB/TrEMBL
      A0A3Q2U2K2, A0A8V0YU62

    12. XM_046927382.1 → XP_046783338.1  epsin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YU62

    13. XM_046927381.1 → XP_046783337.1  epsin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YU62

    14. XM_046927383.1 → XP_046783339.1  epsin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YU62

    15. XM_046927380.1 → XP_046783336.1  epsin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YU62

    16. XM_046927387.1 → XP_046783343.1  epsin-2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q2UI02, A0A8V0YU62

    17. XM_046927393.1 → XP_046783349.1  epsin-2 isoform X5

      UniProtKB/TrEMBL
      A0A3Q3B230, A0A8V0Z104
    Nucleotide Protein Strain
    Heading Accession and Version

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