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    UPF2 UPF2 regulator of nonsense mediated mRNA decay [ Gallus gallus (chicken) ]

    Gene ID: 419100, updated on 17-Aug-2024

    Summary

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    Official Symbol
    UPF2provided by CGNC
    Official Full Name
    UPF2 regulator of nonsense mediated mRNA decayprovided by CGNC
    Primary source
    CGNC:5054
    See related
    Ensembl:ENSGALG00010005814
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See UPF2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (6805166..6855424, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (6922947..6972579, complement)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121107961 Neighboring gene proline and serine rich 2 Neighboring gene dehydrogenase E1 and transketolase domain containing 1 Neighboring gene Sec61 translocon alpha 2 subunit

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of exon-exon junction complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    regulator of nonsense transcripts 2
    Names
    UPF2 regulator of nonsense transcripts homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      6805166..6855424 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015297667.4 → XP_015153153.1  regulator of nonsense transcripts 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XJ43
      Related
      ENSGALP00010008183.1, ENSGALT00010013862.1
      Conserved Domains (4) summary
      smart00543
      Location:571 → 758
      MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)
      pfam02854
      Location:776 → 986
      MIF4G; MIF4G domain
      pfam04050
      Location:1095 → 1218
      Upf2; Up-frameshift suppressor 2
      cl19727
      Location:357 → 420
      DUF1451; Zinc-ribbon containing domain

    2. XM_015297566.4 → XP_015153052.1  regulator of nonsense transcripts 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XJ43, A0A8V0XT80
      Related
      ENSGALP00010008181.1, ENSGALT00010013859.1
      Conserved Domains (4) summary
      smart00543
      Location:592 → 779
      MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)
      pfam02854
      Location:797 → 1007
      MIF4G; MIF4G domain
      pfam04050
      Location:1116 → 1239
      Upf2; Up-frameshift suppressor 2
      cl19727
      Location:357 → 420
      DUF1451; Zinc-ribbon containing domain

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      6922947..6972579 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040659109.2 → XP_040515043.1  regulator of nonsense transcripts 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XJ43
      Conserved Domains (4) summary
      smart00543
      Location:571 → 758
      MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)
      pfam02854
      Location:776 → 986
      MIF4G; MIF4G domain
      pfam04050
      Location:1095 → 1218
      Upf2; Up-frameshift suppressor 2
      cl19727
      Location:357 → 420
      DUF1451; Zinc-ribbon containing domain

    2. XM_040659108.2 → XP_040515042.1  regulator of nonsense transcripts 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XJ43, A0A8V0XT80
      Conserved Domains (4) summary
      smart00543
      Location:592 → 779
      MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)
      pfam02854
      Location:797 → 1007
      MIF4G; MIF4G domain
      pfam04050
      Location:1116 → 1239
      Upf2; Up-frameshift suppressor 2
      cl19727
      Location:357 → 420
      DUF1451; Zinc-ribbon containing domain
    Nucleotide Protein Strain
    Heading Accession and Version

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