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    TAL1 TAL bHLH transcription factor 1, erythroid differentiation factor [ Gallus gallus (chicken) ]

    Gene ID: 396298, updated on 3-Dec-2024

    Summary

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    Symbol
    TAL1provided by CGNC
    Full Name
    TAL bHLH transcription factor 1, erythroid differentiation factorprovided by CGNC
    Primary source
    CGNC:16227
    See related
    Ensembl:ENSGALG00010022991
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    SCL
    Orthologs
    human mouse all
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    Genomic context

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    See TAL1 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 8 NC_052539.1 (21597188..21605603, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 8 NC_052580.1 (21605573..21614028, complement)

    Chromosome 8 - NC_052539.1Genomic Context describing neighboring genes Neighboring gene EF-hand calcium binding domain 14 Neighboring gene cytochrome P450, family 4, subfamily B, polypeptide 7 Neighboring gene uncharacterized LOC107054049 Neighboring gene PDZK1 interacting protein 1 Neighboring gene SCL/TAL1 interrupting locus Neighboring gene cytidine/uridine monophosphate kinase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning of the chicken SCL cDNA. Goodwin G, et al. Nucleic Acids Res, 1992 Jan 25. PMID 1741264, Free PMC Article
    2. Definitive erythropoiesis in chicken yolk sac. Nagai H, et al. Dev Dyn, 2008 Nov. PMID 18924232
    3. Analysis of vertebrate SCL loci identifies conserved enhancers. Göttgens B, et al. Nat Biotechnol, 2000 Feb. PMID 10657125
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    T-cell acute lymphocytic leukemia protein 1 homolog
    Names
    Avian SCL
    T-cell acute lymphocytic leukemia 1
    TAL-1
    stem cell protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205352.2 → NP_990683.2  T-cell acute lymphocytic leukemia protein 1 homolog

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000239
      UniProtKB/Swiss-Prot
      P24899
      UniProtKB/TrEMBL
      A0A8V0ZSR7, Q9I9C9
      Related
      ENSGALP00010033868.1, ENSGALT00010055964.1
      Conserved Domains (1) summary
      cd19706
      Location:177 → 241
      bHLH_TS_TAL1; basic helix-loop-helix (bHLH) domain found in T-cell acute lymphocytic leukemia protein 1 (TAL-1) and similar proteins

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052539.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      21597188..21605603 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025152765.3 → XP_025008533.2  T-cell acute lymphocytic leukemia protein 1 homolog isoform X1

      UniProtKB/Swiss-Prot
      P24899
      UniProtKB/TrEMBL
      A0A8V0ZSR7, Q9I9C9
      Related
      ENSGALP00010033877.1, ENSGALT00010055979.1
      Conserved Domains (1) summary
      cd19706
      Location:177 → 241
      bHLH_TS_TAL1; basic helix-loop-helix (bHLH) domain found in T-cell acute lymphocytic leukemia protein 1 (TAL-1) and similar proteins

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052580.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      21605573..21614028 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046922401.1 → XP_046778357.1  T-cell acute lymphocytic leukemia protein 1 homolog isoform X1

      UniProtKB/Swiss-Prot
      P24899
      UniProtKB/TrEMBL
      Q9I9C9
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P24899.1 GenPept UniProtKB/Swiss-Prot:P24899

    Gene LinkOut

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