SPINK5 serine peptidase inhibitor, Kazal type 5 [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: SPINK5provided by CGNC
Official Full Name: serine peptidase inhibitor, Kazal type 5provided by CGNC
Primary source: CGNC:50204
See related: Ensembl:ENSGALG00010014696
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: NS; OI; OIH; NETS; OvoI; LEKTI; LETKI; SPIK5; VAKTI
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Genomic context

Location:: chromosome: 13

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	13	NC_052544.1 (10159597..10169565)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	13	NC_052585.1 (10161846..10171811)

Chromosome 13 - NC_052544.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

OIH plays a vital role in egg quality. The combinations of A4363G and C8937G polymorphisms might be potential advantageous molecular markers for improving Haugh unit of chicken eggs.
Title: Polymorphisms in the ovoinhibitor gene (OIH) and their association with egg quality of Xinhua E-strain chickens.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: ovoinhibitor

Names: lympho-epithelial Kazal-type-related inhibitor; lymphoepithelial Kazal-type-related inhibitor; serine protease inhibitor, Kazal type 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001030612.3 → NP_001025783.3 ovoinhibitor precursor

Status: VALIDATED

Source sequence(s)

JAENSK010000256

UniProtKB/TrEMBL

A0A8V0YW85

Related

ENSGALP00010020558.1, ENSGALT00010035316.1

Conserved Domains (2) summary

pfam00050
Location:159 → 216

Kazal_1; Kazal-type serine protease inhibitor domain

cl00097
Location:306 → 347

KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...