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    ISCU iron-sulfur cluster assembly enzyme [ Gallus gallus (chicken) ]

    Gene ID: 416891, updated on 17-Aug-2024

    Summary

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    Symbol
    ISCUprovided by CGNC
    Full Name
    iron-sulfur cluster assembly enzymeprovided by CGNC
    Primary source
    CGNC:3614
    See related
    Ensembl:ENSGALG00010022525
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See ISCU in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 15 NC_052546.1 (6536199..6538364)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 15 NC_052587.1 (6546716..6548876)

    Chromosome 15 - NC_052546.1Genomic Context describing neighboring genes Neighboring gene chemerin chemokine-like receptor 1 Neighboring gene FIC domain containing Neighboring gene squamous cell carcinoma antigen recognized by T-cells 3 Neighboring gene transmembrane protein 119 Neighboring gene selectin P ligand Neighboring gene coronin 1C

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 2 iron, 2 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ferrous iron binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular iron ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in iron-sulfur cluster assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    iron-sulfur cluster assembly enzyme ISCU, mitochondrial
    Names
    iron-sulfur cluster scaffold homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052546.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      6536199..6538364
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003642182.6 → XP_003642230.3  iron-sulfur cluster assembly enzyme ISCU, mitochondrial

      UniProtKB/TrEMBL
      A0A8V0ZQM8
      Related
      ENSGALP00010033137.1, ENSGALT00010054824.1
      Conserved Domains (1) summary
      PRK11325
      Location:24 → 146
      PRK11325; scaffold protein; Provisional

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052587.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      6546716..6548876
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040684689.2 → XP_040540623.1  iron-sulfur cluster assembly enzyme ISCU, mitochondrial

      UniProtKB/TrEMBL
      A0A8V0ZQM8
      Conserved Domains (1) summary
      PRK11325
      Location:24 → 146
      PRK11325; scaffold protein; Provisional
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials