ORC6 origin recognition complex subunit 6 [Gallus gallus (chicken)] - Gene

Summary

Symbol: ORC6provided by CGNC
Full Name: origin recognition complex subunit 6provided by CGNC
Primary source: CGNC:3194
See related: Ensembl:ENSGALG00010023733
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: ORC6L
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	11	NC_052542.1 (7467581..7472775, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	11	NC_052583.1 (7810119..7815312, complement)

Chromosome 11 - NC_052542.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The cell cycle-related gene ORC6L showed higher expression in the cultured chicken primordial germ cells than that of cultured chicken embryonic fibroblast cells.
Title: Gene pathways and cell cycle-related genes in cultured avian primordial germ cells.
Results exemplify N-end rule degrons as tools to unravel functions of a single protein, Orc6, during different phases of the vertebrate cell cycle.
Title: A vertebrate N-end rule degron reveals that Orc6 is required in mitosis for daughter cell abscission.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in DNA replication	IEA Inferred from Electronic Annotation more info	PubMed
involved_in DNA replication initiation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of nuclear origin of replication recognition complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: origin recognition complex subunit 6

Names: origin recognition complex, subunit 6 like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001277719.2 → NP_001264648.1 origin recognition complex subunit 6 isoform 1

Status: VALIDATED

Description

Transcript Variant: This variant (1) encodes the longer isoform (1).

Source sequence(s)

JAENSK010000248

UniProtKB/TrEMBL

A0A8V0ZNY5, A0A8V1A1P6

Related

ENSGALP00010035114.1, ENSGALT00010057866.1

Conserved Domains (3) summary

cd11583
Location:95 → 186

Orc6_mid; Middle domain of the origin recognition complex subunit 6

cd16075
Location:202 → 249

ORC6_CTD; C-terminal domain of the eukaryotic origin recognition complex subunit ORC6

cl21687
Location:6 → 93

Orc6_mid; Middle domain of the origin recognition complex subunit 6
NM_001277720.1 → NP_001264649.1 origin recognition complex subunit 6 isoform 2

Status: VALIDATED

Description

Transcript Variant: This variant (2) lacks the 3'-most intron compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.

Source sequence(s)

BU244351, BU468253, BX932635, CR385961

UniProtKB/TrEMBL

A0A8V0ZXR5, A0A8V1A1P6

Related

ENSGALP00010035117.1, ENSGALT00010057873.1

Conserved Domains (3) summary

cd11583
Location:95 → 186

Orc6_mid; Middle domain of the origin recognition complex subunit 6

cd16075
Location:202 → 249

ORC6_CTD; C-terminal domain of the eukaryotic origin recognition complex subunit ORC6

cl21687
Location:6 → 93

Orc6_mid; Middle domain of the origin recognition complex subunit 6

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052542.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

7467581..7472775 complement

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GenBank, FASTA, Sequence Viewer (Graphics)