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    RGS3 regulator of G-protein signaling 3 [ Gallus gallus (chicken) ]

    Gene ID: 395110, updated on 3-Dec-2024

    Summary

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    Symbol
    RGS3provided by CGNC
    Full Name
    regulator of G-protein signaling 3provided by CGNC
    Primary source
    CGNC:6745
    See related
    Ensembl:ENSGALG00010027912
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See RGS3 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 17 NC_052548.1 (2040097..2104430, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 17 NC_052589.1 (1448405..1512724, complement)

    Chromosome 17 - NC_052548.1Genomic Context describing neighboring genes Neighboring gene transfer RNA threonine (anticodon AGU) Neighboring gene uncharacterized LOC101749962 Neighboring gene DNA polymerase epsilon 3, accessory subunit Neighboring gene aminolevulinate dehydratase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. RGS3 mediates a calcium-dependent termination of G protein signaling in sensory neurons. Tosetti P, et al. Proc Natl Acad Sci U S A, 2003 Jun 10. PMID 12771384, Free PMC Article
    2. An expressed sequence tag analysis of the chicken reproductive tract transcriptome. Froman DP, et al. Poult Sci, 2006 Aug. PMID 16903475
    3. Chicken genomics resource: sequencing and annotation of 35,407 ESTs from single and multiple tissue cDNA libraries and CAP3 assembly of a chicken gene index. Carre W, et al. Physiol Genomics, 2006 May 16. PMID 16554550
    4. A comprehensive collection of chicken cDNAs. Boardman PE, et al. Curr Biol, 2002 Nov 19. PMID 12445392
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    regulator of G-protein signaling 3
    Names
    regulator of G-protein signalling 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001048051.3 → NP_001041516.1  regulator of G-protein signaling 3 RGS3s isoform

      See identical proteins and their annotated locations for NP_001041516.1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000308
      UniProtKB/TrEMBL
      Q7SYI0, Q7SYI1
      Conserved Domains (1) summary
      cd08713
      Location:284 → 397
      RGS_RGS3; Regulator of G protein signaling (RGS) domain found in the RGS3 protein

    2. NM_001281935.3 → NP_001268864.1  regulator of G-protein signaling 3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000308
      UniProtKB/TrEMBL
      A0A1D5P7S3, Q7SYI0
      Related
      ENSGALP00010041410.1, ENSGALT00010067667.1
      Conserved Domains (1) summary
      cd08713
      Location:291 → 404
      RGS_RGS3; Regulator of G protein signaling (RGS) domain found in the RGS3 protein

    3. NM_001281937.3 → NP_001268866.1  regulator of G-protein signaling 3 isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000308
      UniProtKB/TrEMBL
      Q7SYI3
      Conserved Domains (1) summary
      cd08713
      Location:86 → 199
      RGS_RGS3; Regulator of G protein signaling (RGS) domain found in the RGS3 protein

    4. NM_001397769.1 → NP_001384698.1  regulator of G-protein signaling 3 isoform 5

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000308
      UniProtKB/TrEMBL
      Q7SYI3
      Conserved Domains (1) summary
      cd08713
      Location:76 → 189
      RGS_RGS3; Regulator of G protein signaling (RGS) domain found in the RGS3 protein

    5. NM_204459.4 → NP_989790.2  regulator of G-protein signaling 3 RGS3L isoform

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000308
      UniProtKB/TrEMBL
      Q7SYH9
      Conserved Domains (3) summary
      cd08713
      Location:675 → 788
      RGS_RGS3; Regulator of G protein signaling (RGS) domain found in the RGS3 protein
      COG0265
      Location:38 → 93
      DegQ; Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]
      cd00992
      Location:17 → 91
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052548.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      2040097..2104430 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015279301.4 → XP_015134787.2  regulator of G-protein signaling 3 isoform X1

      UniProtKB/TrEMBL
      Q7SYH9
      Conserved Domains (3) summary
      cd08685
      Location:29 → 148
      C2_RGS-like; C2 domain of the Regulator Of G-Protein Signaling (RGS) family
      cd08713
      Location:850 → 963
      RGS_RGS3; Regulator of G protein signaling (RGS) domain found in the RGS3 protein
      cd00992
      Location:194 → 266
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

    2. XM_040648931.2 → XP_040504865.1  regulator of G-protein signaling 3 isoform X6

      UniProtKB/TrEMBL
      Q7SYH9
      Conserved Domains (3) summary
      cd08713
      Location:826 → 939
      RGS_RGS3; Regulator of G protein signaling (RGS) domain found in the RGS3 protein
      cd00992
      Location:170 → 242
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl14603
      Location:22 → 124
      C2; C2 domain

    3. XM_040648932.2 → XP_040504866.1  regulator of G-protein signaling 3 isoform X2

      UniProtKB/TrEMBL
      Q7SYH9
      Conserved Domains (3) summary
      cd08713
      Location:804 → 917
      RGS_RGS3; Regulator of G protein signaling (RGS) domain found in the RGS3 protein
      cd00992
      Location:148 → 220
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl14603
      Location:1 → 102
      C2; C2 domain

    4. XM_046901639.1 → XP_046757595.1  regulator of G-protein signaling 3 isoform X3

      UniProtKB/TrEMBL
      Q7SYH9

    5. XM_040648933.2 → XP_040504867.1  regulator of G-protein signaling 3 isoform X5

      UniProtKB/TrEMBL
      Q7SYI0, Q7SYI1
      Conserved Domains (1) summary
      cd08713
      Location:284 → 397
      RGS_RGS3; Regulator of G protein signaling (RGS) domain found in the RGS3 protein

    6. XM_046901640.1 → XP_046757596.1  regulator of G-protein signaling 3 isoform X4

      UniProtKB/TrEMBL
      A0A1D5P7S3, Q7SYI0

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052589.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      1448405..1512724 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046928692.1 → XP_046784648.1  regulator of G-protein signaling 3 isoform X1

      UniProtKB/TrEMBL
      Q7SYH9

    2. XM_046928694.1 → XP_046784650.1  regulator of G-protein signaling 3 isoform X2

      UniProtKB/TrEMBL
      Q7SYH9

    3. XM_046928693.1 → XP_046784649.1  regulator of G-protein signaling 3 isoform X2

      UniProtKB/TrEMBL
      Q7SYH9

    4. XM_046928695.1 → XP_046784651.1  regulator of G-protein signaling 3 isoform X3

      UniProtKB/TrEMBL
      Q7SYH9

    5. XM_046928697.1 → XP_046784653.1  regulator of G-protein signaling 3 isoform X5

      UniProtKB/TrEMBL
      Q7SYI0, Q7SYI1

    6. XM_046928696.1 → XP_046784652.1  regulator of G-protein signaling 3 isoform X4

      UniProtKB/TrEMBL
      A0A1D5P7S3, Q7SYI0

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001048052.1: Suppressed sequence

      Description
      NM_001048052.1: This RefSeq was temporarily suppressed because the CDS was partial.

    2. NM_001048053.1: Suppressed sequence

      Description
      NM_001048053.1: This RefSeq was temporarily suppressed because the CDS was partial.
    Nucleotide Protein Strain
    Heading Accession and Version

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