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    RIPK2 receptor interacting serine/threonine kinase 2 [ Gallus gallus (chicken) ]

    Gene ID: 420215, updated on 17-Aug-2024

    Summary

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    Symbol
    RIPK2provided by CGNC
    Full Name
    receptor interacting serine/threonine kinase 2provided by CGNC
    Primary source
    CGNC:11860
    See related
    Ensembl:ENSGALG00010012401
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See RIPK2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (123855080..123873107)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (124048859..124066885)

    Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene matrix metallopeptidase 16 Neighboring gene uncharacterized LOC121110007 Neighboring gene uncharacterized LOC101752047 Neighboring gene solute carrier family 7 member 7 Neighboring gene oxidative stress induced growth inhibitor family member 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Splenic gene expression profiling in White Leghorn layer inoculated with the Salmonella enterica serovar Enteritidis. Wu G, et al. Anim Genet, 2015 Dec. PMID 26358731
    2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables JUN kinase kinase kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    receptor-interacting serine/threonine-protein kinase 2
    NP_001026114.1
    NP_001383534.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001030943.2 → NP_001026114.1  receptor-interacting serine/threonine-protein kinase 2 isoform 1

      See identical proteins and their annotated locations for NP_001026114.1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000044
      UniProtKB/TrEMBL
      Q5ZJT6
      Related
      ENSGALP00010017289.1, ENSGALT00010029710.1
      Conserved Domains (3) summary
      cd08786
      Location:480 → 566
      CARD_RIP2_CARD3; Caspase activation and recruitment domain of Receptor Interacting Protein 2
      smart00220
      Location:28 → 292
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14026
      Location:27 → 308
      STKc_RIP2; Catalytic domain of the Serine/Threonine kinase, Receptor Interacting Protein 2

    2. NM_001396605.1 → NP_001383534.1  receptor-interacting serine/threonine-protein kinase 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000044
      UniProtKB/TrEMBL
      A0A8V0YED1
      Related
      ENSGALP00010017286.1, ENSGALT00010029705.1
      Conserved Domains (2) summary
      cd08786
      Location:456 → 542
      CARD_RIP2_CARD3; Caspase activation and recruitment domain of Receptor Interacting Protein 2
      cd14026
      Location:27 → 308
      STKc_RIP2; Catalytic domain of the Serine/Threonine kinase, Receptor Interacting Protein 2

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      123855080..123873107
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      124048859..124066885
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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    Research Materials