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    ATG4B autophagy related 4B cysteine peptidase [ Gallus gallus (chicken) ]

    Gene ID: 404750, updated on 3-Dec-2024

    Summary

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    Symbol
    ATG4Bprovided by CGNC
    Full Name
    autophagy related 4B cysteine peptidaseprovided by CGNC
    Primary source
    CGNC:49878
    See related
    Ensembl:ENSGALG00010024918
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    APG4B
    Orthologs
    human mouse all
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    Genomic context

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    See ATG4B in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 9 NC_052540.1 (4446762..4466350, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 9 NC_052581.1 (4279654..4299266, complement)

    Chromosome 9 - NC_052540.1Genomic Context describing neighboring genes Neighboring gene inhibitor of growth family member 5 Neighboring gene deoxythymidylate kinase Neighboring gene THAP domain containing 4 Neighboring gene espin-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Processing of a pestivirus protein by a cellular protease specific for light chain 3 of microtubule-associated proteins. Fricke J, et al. J Virol, 2004 Jun. PMID 15140988, Free PMC Article
    2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein-phosphatidylethanolamide deconjugating activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cysteine protease ATG4B
    Names
    APG4 autophagy 4 homolog B
    ATG4 autophagy related 4 homolog B
    AUT2B
    autophagin-2B
    autophagy-related cysteine endopeptidase 2B
    autophagy-related protein 4 homolog B
    cAut2B
    NP_001385364.1
    NP_998738.1
    XP_015132333.1
    XP_046779642.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001398435.1 → NP_001385364.1  cysteine protease ATG4B isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000240
      Conserved Domains (1) summary
      pfam03416
      Location:1 → 262
      Peptidase_C54; Peptidase family C54

    2. NM_213573.2 → NP_998738.1  cysteine protease ATG4B isoform 1

      See identical proteins and their annotated locations for NP_998738.1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000240
      UniProtKB/Swiss-Prot
      Q5ZK72, Q6PZ02
      UniProtKB/TrEMBL
      A0A8V1A8C7
      Related
      ENSGALP00010037617.1, ENSGALT00010060860.1
      Conserved Domains (1) summary
      pfam03416
      Location:39 → 335
      Peptidase_C54; Peptidase family C54

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052540.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      4446762..4466350 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015276847.4 → XP_015132333.1  cysteine protease ATG4B isoform X1

      UniProtKB/TrEMBL
      A0A8V1A8B8, A0A8V1A8C7
      Related
      ENSGALP00010037614.1, ENSGALT00010060857.1
      Conserved Domains (1) summary
      pfam03416
      Location:44 → 340
      Peptidase_C54; Peptidase family C54

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052581.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      4279654..4299266 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046923686.1 → XP_046779642.1  cysteine protease ATG4B isoform X1

      UniProtKB/TrEMBL
      A0A8V1A8B8, A0A8V1A8C7
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6PZ02.1 GenPept UniProtKB/Swiss-Prot:Q6PZ02

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.