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    SLC24A2 solute carrier family 24 member 2 [ Gallus gallus (chicken) ]

    Gene ID: 414891, updated on 3-Dec-2024

    Summary

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    Symbol
    SLC24A2provided by CGNC
    Full Name
    solute carrier family 24 member 2provided by CGNC
    Primary source
    CGNC:11219
    See related
    Ensembl:ENSGALG00010016336
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    NCKX
    Orthologs
    human mouse all
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    Genomic context

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    See SLC24A2 in Genome Data Viewer
    Location:
    chromosome: Z
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (34235415..34345782, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (34235415..34345782, complement)

    Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene alkaline ceramidase 2 Neighboring gene ribosomal protein S6 Neighboring gene uncharacterized LOC107052289 Neighboring gene MLLT3, super elongation complex subunit Neighboring gene uncharacterized LOC107052276 Neighboring gene focadhesin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning and functional expression of the potassium-dependent sodium-calcium exchanger from human and chicken retinal cone photoreceptors. Prinsen CF, et al. J Neurosci, 2000 Feb 15. PMID 10662833, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium, potassium:sodium antiporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular calcium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in long-term synaptic depression IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in long-term synaptic potentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sodium/potassium/calcium exchanger 2
    Names
    Na(+)/K(+)/Ca(2+)-exchange protein 2
    cone potassium-dependent, sodium-calcium exchanger
    retinal cone Na-Ca+K exchanger
    solute carrier family 24 (sodium/potassium/calcium exchanger), member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001001772.2 → NP_001001772.2  sodium/potassium/calcium exchanger 2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000093
      UniProtKB/Swiss-Prot
      Q9IAL6, Q9IAL7
      UniProtKB/TrEMBL
      F1NZT1
      Conserved Domains (1) summary
      TIGR00927
      Location:117 → 634
      2A1904; K+-dependent Na+/Ca+ exchanger

    2. NM_001397109.1 → NP_001384038.1  sodium/potassium/calcium exchanger 2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000093
      UniProtKB/Swiss-Prot
      Q9IAL6, Q9IAL7
      UniProtKB/TrEMBL
      F1NZT1
      Conserved Domains (1) summary
      TIGR00927
      Location:117 → 634
      2A1904; K+-dependent Na+/Ca+ exchanger

    3. NM_001397110.1 → NP_001384039.1  sodium/potassium/calcium exchanger 2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000093
      UniProtKB/Swiss-Prot
      Q9IAL6, Q9IAL7
      UniProtKB/TrEMBL
      F1NZT1
      Conserved Domains (1) summary
      TIGR00927
      Location:117 → 634
      2A1904; K+-dependent Na+/Ca+ exchanger

    4. NM_001397111.1 → NP_001384040.1  sodium/potassium/calcium exchanger 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000093
      UniProtKB/Swiss-Prot
      Q9IAL6, Q9IAL7
      UniProtKB/TrEMBL
      A0A1L1RQA3
      Conserved Domains (1) summary
      TIGR00927
      Location:117 → 651
      2A1904; K+-dependent Na+/Ca+ exchanger

    5. NM_001397112.1 → NP_001384041.1  sodium/potassium/calcium exchanger 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000093
      UniProtKB/Swiss-Prot
      Q9IAL6, Q9IAL7
      UniProtKB/TrEMBL
      A0A1L1RQA3
      Conserved Domains (1) summary
      TIGR00927
      Location:117 → 651
      2A1904; K+-dependent Na+/Ca+ exchanger

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      34235415..34345782 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046905289.1 → XP_046761245.1  sodium/potassium/calcium exchanger 2 isoform X4

      UniProtKB/Swiss-Prot
      Q9IAL6, Q9IAL7
      UniProtKB/TrEMBL
      F1NZT1

    2. XM_040655480.2 → XP_040511414.1  sodium/potassium/calcium exchanger 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YX93
      Conserved Domains (1) summary
      TIGR00927
      Location:117 → 621
      2A1904; K+-dependent Na+/Ca+ exchanger

    3. XM_040655478.2 → XP_040511412.1  sodium/potassium/calcium exchanger 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YX93
      Related
      ENSGALP00010022677.1, ENSGALT00010039316.1
      Conserved Domains (1) summary
      TIGR00927
      Location:117 → 638
      2A1904; K+-dependent Na+/Ca+ exchanger

    4. XM_015280084.4 → XP_015135570.1  sodium/potassium/calcium exchanger 2 isoform X1

      UniProtKB/Swiss-Prot
      Q9IAL6, Q9IAL7
      UniProtKB/TrEMBL
      A0A1L1RQA3
      Conserved Domains (1) summary
      TIGR00927
      Location:117 → 651
      2A1904; K+-dependent Na+/Ca+ exchanger

    5. XM_046905290.1 → XP_046761246.1  sodium/potassium/calcium exchanger 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YX93

    6. XM_046905287.1 → XP_046761243.1  sodium/potassium/calcium exchanger 2 isoform X4

      UniProtKB/Swiss-Prot
      Q9IAL6, Q9IAL7
      UniProtKB/TrEMBL
      F1NZT1
      Related
      ENSGALP00010022687.1, ENSGALT00010039329.1

    7. XM_046905291.1 → XP_046761247.1  sodium/potassium/calcium exchanger 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YX93

    8. XM_040655477.2 → XP_040511411.1  sodium/potassium/calcium exchanger 2 isoform X1

      UniProtKB/Swiss-Prot
      Q9IAL6, Q9IAL7
      UniProtKB/TrEMBL
      A0A1L1RQA3
      Conserved Domains (1) summary
      TIGR00927
      Location:117 → 651
      2A1904; K+-dependent Na+/Ca+ exchanger

    9. XM_046905288.1 → XP_046761244.1  sodium/potassium/calcium exchanger 2 isoform X4

      UniProtKB/Swiss-Prot
      Q9IAL6, Q9IAL7
      UniProtKB/TrEMBL
      F1NZT1

    10. XM_046905286.1 → XP_046761242.1  sodium/potassium/calcium exchanger 2 isoform X1

      UniProtKB/Swiss-Prot
      Q9IAL6, Q9IAL7
      UniProtKB/TrEMBL
      A0A1L1RQA3
      Related
      ENSGALP00010022683.1, ENSGALT00010039324.1

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      34235415..34345782 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046934936.1 → XP_046790892.1  sodium/potassium/calcium exchanger 2 isoform X4

      UniProtKB/Swiss-Prot
      Q9IAL6, Q9IAL7
      UniProtKB/TrEMBL
      F1NZT1

    2. XM_046934933.1 → XP_046790889.1  sodium/potassium/calcium exchanger 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YX93

    3. XM_046934932.1 → XP_046790888.1  sodium/potassium/calcium exchanger 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YX93

    4. XM_046934929.1 → XP_046790885.1  sodium/potassium/calcium exchanger 2 isoform X1

      UniProtKB/Swiss-Prot
      Q9IAL6, Q9IAL7
      UniProtKB/TrEMBL
      A0A1L1RQA3

    5. XM_046934937.1 → XP_046790893.1  sodium/potassium/calcium exchanger 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YX93

    6. XM_046934934.1 → XP_046790890.1  sodium/potassium/calcium exchanger 2 isoform X4

      UniProtKB/Swiss-Prot
      Q9IAL6, Q9IAL7
      UniProtKB/TrEMBL
      F1NZT1

    7. XM_046934938.1 → XP_046790894.1  sodium/potassium/calcium exchanger 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YX93

    8. XM_046934930.1 → XP_046790886.1  sodium/potassium/calcium exchanger 2 isoform X1

      UniProtKB/Swiss-Prot
      Q9IAL6, Q9IAL7
      UniProtKB/TrEMBL
      A0A1L1RQA3

    9. XM_046934935.1 → XP_046790891.1  sodium/potassium/calcium exchanger 2 isoform X4

      UniProtKB/Swiss-Prot
      Q9IAL6, Q9IAL7
      UniProtKB/TrEMBL
      F1NZT1

    10. XM_046934931.1 → XP_046790887.1  sodium/potassium/calcium exchanger 2 isoform X1

      UniProtKB/Swiss-Prot
      Q9IAL6, Q9IAL7
      UniProtKB/TrEMBL
      A0A1L1RQA3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9IAL7.1 GenPept UniProtKB/Swiss-Prot:Q9IAL7

    Gene LinkOut

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