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    TLK1 tousled like kinase 1 [ Gallus gallus (chicken) ]

    Gene ID: 424155, updated on 3-Dec-2024

    Summary

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    Symbol
    TLK1provided by CGNC
    Full Name
    tousled like kinase 1provided by CGNC
    Primary source
    CGNC:52142
    See related
    Ensembl:ENSGALG00010023211
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See TLK1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    40
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 7 NC_052538.1 (17688454..17792486)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 7 NC_052579.1 (17607719..17711751)

    Chromosome 7 - NC_052538.1Genomic Context describing neighboring genes Neighboring gene methyltransferase like 8 Neighboring gene cytochrome b reductase 1 Neighboring gene DDB1 and CUL4 associated factor 17 Neighboring gene golgi reassembly stacking protein 2 Neighboring gene uncharacterized LOC121111327

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromosome segregation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase tousled-like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052538.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      17688454..17792486
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015289759.4 → XP_015145245.1  serine/threonine-protein kinase tousled-like 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZU22
      Conserved Domains (1) summary
      cd14040
      Location:398 → 696
      STKc_TLK1; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 1

    2. XM_046944076.1 → XP_046800032.1  serine/threonine-protein kinase tousled-like 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZU22

    3. XM_046944068.1 → XP_046800024.1  serine/threonine-protein kinase tousled-like 1 isoform X5

      UniProtKB/TrEMBL
      A0A8V0ZS33, A0A8V0ZU22
      Related
      ENSGALP00010034349.1, ENSGALT00010056607.1

    4. XM_040704186.2 → XP_040560120.1  serine/threonine-protein kinase tousled-like 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZU22
      Related
      ENSGALP00010034336.1, ENSGALT00010056594.1
      Conserved Domains (1) summary
      cd14040
      Location:398 → 696
      STKc_TLK1; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 1

    5. XM_426581.8 → XP_426581.5  serine/threonine-protein kinase tousled-like 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZLU3, A0A8V0ZU22
      Related
      ENSGALP00010034342.1, ENSGALT00010056600.1
      Conserved Domains (2) summary
      PHA03307
      Location:2 → 191
      PHA03307; transcriptional regulator ICP4; Provisional
      cd14040
      Location:447 → 745
      STKc_TLK1; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 1

    6. XM_046944069.1 → XP_046800025.1  serine/threonine-protein kinase tousled-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PFE5, A0A8V0ZU22

    7. XM_046944070.1 → XP_046800026.1  serine/threonine-protein kinase tousled-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PFE5, A0A8V0ZU22

    8. XM_046944074.1 → XP_046800030.1  serine/threonine-protein kinase tousled-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PFE5, A0A8V0ZU22

    9. XM_046944077.1 → XP_046800033.1  serine/threonine-protein kinase tousled-like 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZU22

    10. XM_046944071.1 → XP_046800027.1  serine/threonine-protein kinase tousled-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PFE5, A0A8V0ZU22

    11. XM_046944075.1 → XP_046800031.1  serine/threonine-protein kinase tousled-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PFE5, A0A8V0ZU22

    12. XM_046944078.1 → XP_046800034.1  serine/threonine-protein kinase tousled-like 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZU22

    13. XM_004942747.5 → XP_004942804.1  serine/threonine-protein kinase tousled-like 1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZS22, A0A8V0ZU22
      Related
      ENSGALP00010034339.1, ENSGALT00010056597.1
      Conserved Domains (1) summary
      cd14040
      Location:411 → 709
      STKc_TLK1; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 1

    14. XM_046944073.1 → XP_046800029.1  serine/threonine-protein kinase tousled-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PFE5, A0A8V0ZU22
      Related
      ENSGALP00010034333.1, ENSGALT00010056591.1

    RNA

    1. XR_006939905.1 RNA Sequence

    2. XR_005861656.2 RNA Sequence

    3. XR_005861659.2 RNA Sequence

    4. XR_006939903.1 RNA Sequence

    5. XR_005861661.2 RNA Sequence

    6. XR_005861665.2 RNA Sequence

    7. XR_005861657.2 RNA Sequence

    8. XR_005861664.2 RNA Sequence

    9. XR_005861650.2 RNA Sequence

    10. XR_003076230.3 RNA Sequence

    11. XR_006939902.1 RNA Sequence

    12. XR_005861651.2 RNA Sequence

    13. XR_006939904.1 RNA Sequence

    14. XR_005861655.2 RNA Sequence

    15. XR_005861662.2 RNA Sequence

    16. XR_005861670.2 RNA Sequence

    17. XR_005861666.2 RNA Sequence

    18. XR_005861673.2 RNA Sequence

    19. XR_005861671.2 RNA Sequence

    20. XR_005861676.2 RNA Sequence

    21. XR_005861654.2 RNA Sequence

    22. XR_003076241.3 RNA Sequence

    23. XR_005861663.2 RNA Sequence

    24. XR_005861672.2 RNA Sequence

    25. XR_005861660.2 RNA Sequence

    26. XR_005861667.2 RNA Sequence

    27. XR_005861674.2 RNA Sequence

    28. XR_005861658.2 RNA Sequence

    29. XR_005861669.2 RNA Sequence

    30. XR_005861675.2 RNA Sequence

    31. XR_005861668.2 RNA Sequence

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052579.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      17607719..17711751
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040676717.2 → XP_040532651.1  serine/threonine-protein kinase tousled-like 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZU22
      Conserved Domains (1) summary
      cd14040
      Location:398 → 696
      STKc_TLK1; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 1

    2. XM_046921945.1 → XP_046777901.1  serine/threonine-protein kinase tousled-like 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZU22

    3. XM_046921948.1 → XP_046777904.1  serine/threonine-protein kinase tousled-like 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZU22

    4. XM_046921943.1 → XP_046777899.1  serine/threonine-protein kinase tousled-like 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZU22

    5. XM_040676716.2 → XP_040532650.1  serine/threonine-protein kinase tousled-like 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZU22
      Conserved Domains (1) summary
      cd14040
      Location:398 → 696
      STKc_TLK1; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 1

    6. XM_040676712.2 → XP_040532646.1  serine/threonine-protein kinase tousled-like 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZLU3, A0A8V0ZU22
      Conserved Domains (2) summary
      PHA03307
      Location:2 → 191
      PHA03307; transcriptional regulator ICP4; Provisional
      cd14040
      Location:447 → 745
      STKc_TLK1; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 1

    7. XM_046921938.1 → XP_046777894.1  serine/threonine-protein kinase tousled-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PFE5, A0A8V0ZU22

    8. XM_046921939.1 → XP_046777895.1  serine/threonine-protein kinase tousled-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PFE5, A0A8V0ZU22

    9. XM_046921940.1 → XP_046777896.1  serine/threonine-protein kinase tousled-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PFE5, A0A8V0ZU22

    10. XM_046921942.1 → XP_046777898.1  serine/threonine-protein kinase tousled-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PFE5, A0A8V0ZU22

    11. XM_046921947.1 → XP_046777903.1  serine/threonine-protein kinase tousled-like 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZU22

    12. XM_040676715.2 → XP_040532649.1  serine/threonine-protein kinase tousled-like 1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZS22, A0A8V0ZU22
      Conserved Domains (1) summary
      cd14040
      Location:411 → 709
      STKc_TLK1; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 1

    13. XM_046921941.1 → XP_046777897.1  serine/threonine-protein kinase tousled-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PFE5, A0A8V0ZU22

    14. XM_046921946.1 → XP_046777902.1  serine/threonine-protein kinase tousled-like 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZU22

    RNA

    1. XR_006935331.1 RNA Sequence

    2. XR_005851923.2 RNA Sequence

    3. XR_005851926.2 RNA Sequence

    4. XR_006935329.1 RNA Sequence

    5. XR_005851928.2 RNA Sequence

    6. XR_005851933.2 RNA Sequence

    7. XR_005851924.2 RNA Sequence

    8. XR_005851931.2 RNA Sequence

    9. XR_005851917.2 RNA Sequence

    10. XR_005851916.2 RNA Sequence

    11. XR_006935328.1 RNA Sequence

    12. XR_005851918.2 RNA Sequence

    13. XR_006935330.1 RNA Sequence

    14. XR_005851921.2 RNA Sequence

    15. XR_005851929.2 RNA Sequence

    16. XR_005851934.2 RNA Sequence

    17. XR_005851932.2 RNA Sequence

    18. XR_005851939.2 RNA Sequence

    19. XR_005851942.2 RNA Sequence

    20. XR_005851922.2 RNA Sequence

    21. XR_005851943.2 RNA Sequence

    22. XR_005851930.2 RNA Sequence

    23. XR_005851938.2 RNA Sequence

    24. XR_005851927.2 RNA Sequence

    25. XR_005851935.2 RNA Sequence

    26. XR_005851940.2 RNA Sequence

    27. XR_005851925.2 RNA Sequence

    28. XR_005851937.2 RNA Sequence

    29. XR_005851941.2 RNA Sequence

    30. XR_005851936.2 RNA Sequence

    Nucleotide Protein Strain
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