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    PLEKHM2 pleckstrin homology and RUN domain containing M2 [ Gallus gallus (chicken) ]

    Gene ID: 419457, updated on 17-Aug-2024

    Summary

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    Symbol
    PLEKHM2provided by CGNC
    Full Name
    pleckstrin homology and RUN domain containing M2provided by CGNC
    Primary source
    CGNC:2507
    See related
    Ensembl:ENSGALG00010021791
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See PLEKHM2 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 21 NC_052552.1 (4198157..4218451)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 21 NC_052593.1 (4231266..4251562)

    Chromosome 21 - NC_052552.1Genomic Context describing neighboring genes Neighboring gene mechanistic target of rapamycin Neighboring gene angiopoietin like 7 Neighboring gene UbiA prenyltransferase domain containing 1 Neighboring gene solute carrier family 25 member 34 Neighboring gene uncharacterized LOC121107386 Neighboring gene transmembrane protein 82 Neighboring gene filamin binding LIM protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables kinesin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Golgi organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lysosome localization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of membrane tubulation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of protein localization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pleckstrin homology domain-containing family M member 2
    Names
    pleckstrin homology domain containing, family M (with RUN domain) member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052552.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      4198157..4218451
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015297167.4 → XP_015152653.2  pleckstrin homology domain-containing family M member 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZSX3
      Conserved Domains (3) summary
      smart00593
      Location:93 → 156
      RUN; domain involved in Ras-like GTPase signaling
      cd13309
      Location:770 → 872
      PH_SKIP; SifA and kinesin-interacting protein Pleckstrin homology (PH) domain
      pfam03157
      Location:345 → 569
      Glutenin_hmw; High molecular weight glutenin subunit

    2. XM_417616.8 → XP_417616.4  pleckstrin homology domain-containing family M member 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZSX3
      Related
      ENSGALP00010031911.1, ENSGALT00010053005.1
      Conserved Domains (3) summary
      smart00593
      Location:93 → 156
      RUN; domain involved in Ras-like GTPase signaling
      cd13309
      Location:765 → 867
      PH_SKIP; SifA and kinesin-interacting protein Pleckstrin homology (PH) domain
      pfam03157
      Location:345 → 569
      Glutenin_hmw; High molecular weight glutenin subunit

    3. XM_015297168.4 → XP_015152654.2  pleckstrin homology domain-containing family M member 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZSX8
      Related
      ENSGALP00010031916.1, ENSGALT00010053010.1
      Conserved Domains (3) summary
      smart00593
      Location:93 → 156
      RUN; domain involved in Ras-like GTPase signaling
      cd13309
      Location:750 → 852
      PH_SKIP; SifA and kinesin-interacting protein Pleckstrin homology (PH) domain
      pfam03157
      Location:325 → 549
      Glutenin_hmw; High molecular weight glutenin subunit

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052593.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      4231266..4251562
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040689169.2 → XP_040545103.1  pleckstrin homology domain-containing family M member 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZSX3
      Conserved Domains (3) summary
      smart00593
      Location:93 → 156
      RUN; domain involved in Ras-like GTPase signaling
      cd13309
      Location:770 → 872
      PH_SKIP; SifA and kinesin-interacting protein Pleckstrin homology (PH) domain
      pfam03157
      Location:345 → 569
      Glutenin_hmw; High molecular weight glutenin subunit

    2. XM_040689170.2 → XP_040545104.1  pleckstrin homology domain-containing family M member 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZSX3
      Conserved Domains (3) summary
      smart00593
      Location:93 → 156
      RUN; domain involved in Ras-like GTPase signaling
      cd13309
      Location:765 → 867
      PH_SKIP; SifA and kinesin-interacting protein Pleckstrin homology (PH) domain
      pfam03157
      Location:345 → 569
      Glutenin_hmw; High molecular weight glutenin subunit

    3. XM_040689171.2 → XP_040545105.1  pleckstrin homology domain-containing family M member 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZSX8
      Conserved Domains (3) summary
      smart00593
      Location:93 → 156
      RUN; domain involved in Ras-like GTPase signaling
      cd13309
      Location:750 → 852
      PH_SKIP; SifA and kinesin-interacting protein Pleckstrin homology (PH) domain
      pfam03157
      Location:325 → 549
      Glutenin_hmw; High molecular weight glutenin subunit
    Nucleotide Protein
    Heading Accession and Version

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