U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    SMOC1 SPARC related modular calcium binding 1 [ Gallus gallus (chicken) ]

    Gene ID: 768688, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Symbol
    SMOC1provided by CGNC
    Full Name
    SPARC related modular calcium binding 1provided by CGNC
    Primary source
    CGNC:7159
    See related
    Ensembl:ENSGALG00010021485
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See SMOC1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (27230764..27352062, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (27191110..27312365, complement)

    Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene COX16, cytochrome c oxidase assembly homolog Neighboring gene solute carrier family 8 member A3 Neighboring gene solute carrier family 10 member 1 Neighboring gene serine and arginine rich splicing factor 5

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A genome-wide SNP scan reveals two loci associated with the chicken resistance to Marek's disease. Li DF, et al. Anim Genet, 2013 Apr. PMID 22812605
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Up-regulation of SMOC1 in susceptible spleens suggests its important roles in Marek's disease tumorigenesis.
      Title: A genome-wide SNP scan reveals two loci associated with the chicken resistance to Marek's disease.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables extracellular matrix binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables heparin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in basement membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    SPARC-related modular calcium-binding protein 1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      27230764..27352062 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015287582.4 → XP_015143068.1  SPARC-related modular calcium-binding protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZJZ0
      Related
      ENSGALP00010031102.1, ENSGALT00010052090.1
      Conserved Domains (4) summary
      smart00280
      Location:46 → 91
      KAZAL; Kazal type serine protease inhibitors
      cd16240
      Location:319 → 433
      EFh_SPARC_SMOC1; EF-hand, extracellular calcium-binding (EC) motif, found in secreted modular calcium-binding protein 1 (SMOC-1)
      pfam00086
      Location:99 → 162
      Thyroglobulin_1; Thyroglobulin type-1 repeat
      pfam16597
      Location:163 → 223
      Thyroglob_assoc; Thyroglobulin_1 repeat associated disordered domain

    2. XM_004941688.5 → XP_004941745.1  SPARC-related modular calcium-binding protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZJZ0
      Conserved Domains (4) summary
      smart00280
      Location:46 → 91
      KAZAL; Kazal type serine protease inhibitors
      cd16240
      Location:330 → 444
      EFh_SPARC_SMOC1; EF-hand, extracellular calcium-binding (EC) motif, found in secreted modular calcium-binding protein 1 (SMOC-1)
      pfam00086
      Location:99 → 162
      Thyroglobulin_1; Thyroglobulin type-1 repeat
      pfam16597
      Location:163 → 234
      Thyroglob_assoc; Thyroglobulin_1 repeat associated disordered domain

    3. XM_001231760.7 → XP_001231761.2  SPARC-related modular calcium-binding protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZJZ0
      Conserved Domains (4) summary
      smart00280
      Location:46 → 91
      KAZAL; Kazal type serine protease inhibitors
      cd16240
      Location:330 → 444
      EFh_SPARC_SMOC1; EF-hand, extracellular calcium-binding (EC) motif, found in secreted modular calcium-binding protein 1 (SMOC-1)
      pfam00086
      Location:99 → 162
      Thyroglobulin_1; Thyroglobulin type-1 repeat
      pfam16597
      Location:163 → 234
      Thyroglob_assoc; Thyroglobulin_1 repeat associated disordered domain

    4. XM_040702037.2 → XP_040557971.1  SPARC-related modular calcium-binding protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A8V0ZJZ0
      Conserved Domains (3) summary
      cd16240
      Location:261 → 375
      EFh_SPARC_SMOC1; EF-hand, extracellular calcium-binding (EC) motif, found in secreted modular calcium-binding protein 1 (SMOC-1)
      pfam00086
      Location:30 → 93
      Thyroglobulin_1; Thyroglobulin type-1 repeat
      pfam16597
      Location:94 → 165
      Thyroglob_assoc; Thyroglobulin_1 repeat associated disordered domain

    5. XM_040702036.1 → XP_040557970.1  SPARC-related modular calcium-binding protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZJZ0
      Conserved Domains (3) summary
      smart00280
      Location:13 → 58
      KAZAL; Kazal type serine protease inhibitors
      cd00191
      Location:65 → 129
      TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
      cd16240
      Location:297 → 411
      EFh_SPARC_SMOC1; EF-hand, extracellular calcium-binding (EC) motif, found in secreted modular calcium-binding protein 1 (SMOC-1)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      27191110..27312365 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040672050.2 → XP_040527984.1  SPARC-related modular calcium-binding protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZJZ0
      Conserved Domains (4) summary
      smart00280
      Location:46 → 91
      KAZAL; Kazal type serine protease inhibitors
      cd16240
      Location:319 → 433
      EFh_SPARC_SMOC1; EF-hand, extracellular calcium-binding (EC) motif, found in secreted modular calcium-binding protein 1 (SMOC-1)
      pfam00086
      Location:99 → 162
      Thyroglobulin_1; Thyroglobulin type-1 repeat
      pfam16597
      Location:163 → 223
      Thyroglob_assoc; Thyroglobulin_1 repeat associated disordered domain

    2. XM_040672049.2 → XP_040527983.1  SPARC-related modular calcium-binding protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZJZ0
      Conserved Domains (4) summary
      smart00280
      Location:46 → 91
      KAZAL; Kazal type serine protease inhibitors
      cd16240
      Location:330 → 444
      EFh_SPARC_SMOC1; EF-hand, extracellular calcium-binding (EC) motif, found in secreted modular calcium-binding protein 1 (SMOC-1)
      pfam00086
      Location:99 → 162
      Thyroglobulin_1; Thyroglobulin type-1 repeat
      pfam16597
      Location:163 → 234
      Thyroglob_assoc; Thyroglobulin_1 repeat associated disordered domain

    3. XM_040672048.2 → XP_040527982.1  SPARC-related modular calcium-binding protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZJZ0
      Conserved Domains (4) summary
      smart00280
      Location:46 → 91
      KAZAL; Kazal type serine protease inhibitors
      cd16240
      Location:330 → 444
      EFh_SPARC_SMOC1; EF-hand, extracellular calcium-binding (EC) motif, found in secreted modular calcium-binding protein 1 (SMOC-1)
      pfam00086
      Location:99 → 162
      Thyroglobulin_1; Thyroglobulin type-1 repeat
      pfam16597
      Location:163 → 234
      Thyroglob_assoc; Thyroglobulin_1 repeat associated disordered domain

    4. XM_040672053.2 → XP_040527987.1  SPARC-related modular calcium-binding protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A8V0ZJZ0
      Conserved Domains (3) summary
      cd16240
      Location:261 → 375
      EFh_SPARC_SMOC1; EF-hand, extracellular calcium-binding (EC) motif, found in secreted modular calcium-binding protein 1 (SMOC-1)
      pfam00086
      Location:30 → 93
      Thyroglobulin_1; Thyroglobulin type-1 repeat
      pfam16597
      Location:94 → 165
      Thyroglob_assoc; Thyroglobulin_1 repeat associated disordered domain

    5. XM_040672052.1 → XP_040527986.1  SPARC-related modular calcium-binding protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZJZ0
      Conserved Domains (3) summary
      smart00280
      Location:13 → 58
      KAZAL; Kazal type serine protease inhibitors
      cd00191
      Location:65 → 129
      TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
      cd16240
      Location:297 → 411
      EFh_SPARC_SMOC1; EF-hand, extracellular calcium-binding (EC) motif, found in secreted modular calcium-binding protein 1 (SMOC-1)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials