JARID2 jumonji and AT-rich interaction domain containing 2 [Gallus gallus (chicken)] - Gene

Summary

Symbol: JARID2provided by CGNC
Full Name: jumonji and AT-rich interaction domain containing 2provided by CGNC
Primary source: CGNC:9637
See related: Ensembl:ENSGALG00010009678
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: JMJ
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	2	NC_052533.1 (60795173..61001590)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	2	NC_052574.1 (60745408..60951932)

Chromosome 2 - NC_052533.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Based on the findings the authors propose that miR-155 has a prosurvival function that is mediated through the downregulation of targets including JARID2.
Title: Reticuloendotheliosis virus strain T induces miR-155, which targets JARID2 and promotes cell survival.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables histone demethylase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in chromatin remodeling	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: protein Jumonji

Names: jumonji, AT rich interactive domain 2 protein; jumonji/ARID domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001012862.2 → NP_001012880.2 protein Jumonji

Status: VALIDATED

Source sequence(s)

JAENSK010000040

UniProtKB/Swiss-Prot

Q5F363

Conserved Domains (3) summary

smart00545
Location:547 → 588

JmjN; Small domain found in the jumonji family of transcription factors

smart00558
Location:879 → 937

JmjC; A domain family that is part of the cupin metalloenzyme superfamily

cd16870
Location:611 → 722

ARID_JARD2; ARID/BRIGHT DNA binding domain of Jumonji/ARID domain-containing protein 2 (JARID2) and similar proteins