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    PREP prolyl endopeptidase [ Gallus gallus (chicken) ]

    Gene ID: 421785, updated on 3-Dec-2024

    Summary

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    Symbol
    PREPprovided by CGNC
    Full Name
    prolyl endopeptidaseprovided by CGNC
    Primary source
    CGNC:11476
    See related
    Ensembl:ENSGALG00010013317
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See PREP in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (68404211..68502054)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (68185493..68282657)

    Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene PR/SET domain 1 Neighboring gene uncharacterized LOC101751005 Neighboring gene popeye domain containing 3 Neighboring gene blood vessel epicardial substance

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables oligopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    prolyl endopeptidase
    NP_001006410.2
    XP_040553093.1
    XP_046770001.1
    XP_046770002.1
    XP_046770003.1
    XP_046794834.1
    XP_046794835.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001006410.2 → NP_001006410.2  prolyl endopeptidase

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000065
      UniProtKB/TrEMBL
      Q5ZMI7
      Related
      ENSGALP00010018858.1, ENSGALT00010032068.1
      Conserved Domains (1) summary
      COG1505
      Location:26 → 704
      PreP; Prolyl oligopeptidase PreP, S9A serine peptidase family [Amino acid transport and metabolism]

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      68404211..68502054
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040697159.2 → XP_040553093.1  prolyl endopeptidase isoform X1

      UniProtKB/TrEMBL
      A0A8V0YJW0
      Related
      ENSGALP00010018853.1, ENSGALT00010032063.1
      Conserved Domains (1) summary
      COG1505
      Location:34 → 712
      PreP; Prolyl oligopeptidase PreP, S9A serine peptidase family [Amino acid transport and metabolism]

    2. XM_046938879.1 → XP_046794835.1  prolyl endopeptidase isoform X2

      UniProtKB/TrEMBL
      A0A8V0YDG8

    3. XM_046938878.1 → XP_046794834.1  prolyl endopeptidase isoform X2

      UniProtKB/TrEMBL
      A0A8V0YDG8

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      68185493..68282657
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046914045.1 → XP_046770001.1  prolyl endopeptidase isoform X1

      UniProtKB/TrEMBL
      A0A8V0YJW0

    2. XM_046914047.1 → XP_046770003.1  prolyl endopeptidase isoform X2

      UniProtKB/TrEMBL
      A0A8V0YDG8

    3. XM_046914046.1 → XP_046770002.1  prolyl endopeptidase isoform X2

      UniProtKB/TrEMBL
      A0A8V0YDG8
    Nucleotide Protein Strain
    Heading Accession and Version

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