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    C15B12.1 Putative sarcosine oxidase [ Caenorhabditis elegans ]

    Gene ID: 180921, updated on 9-Dec-2024

    Summary

    Official Symbol
    C15B12.1
    Official Full Name
    Putative sarcosine oxidase
    Primary source
    WormBase:WBGene00015783
    Locus tag
    CELE_C15B12.1
    See related
    AllianceGenome:WB:WBGene00015783
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable L-pipecolate oxidase activity and sarcosine oxidase activity. Predicted to be involved in L-lysine catabolic process to acetyl-CoA via L-pipecolate. Predicted to be active in peroxisome. Orthologous to human PIPOX (pipecolic acid and sarcosine oxidase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See C15B12.1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    8
    Sequence:
    Chromosome: X; NC_003284.9 (6476810..6479086)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Autotransporter domain-containing protein Neighboring gene FAD dependent oxidoreductase domain-containing protein Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein;putative muscarinic acetylcholine receptor gar-1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables L-pipecolate oxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables L-pipecolate oxidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables sarcosine oxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables sarcosine oxidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables sarcosine oxidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in L-lysine catabolic process to acetyl-CoA via L-pipecolate IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in L-lysine catabolic process to acetyl-CoA via L-pipecolate ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in peroxisome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in peroxisome ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 

    General protein information

    Preferred Names
    Putative sarcosine oxidase
    NP_509092.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      6476810..6479086
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076691.7NP_509092.2  Putative sarcosine oxidase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509092.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q18006
      Conserved Domains (2) summary
      TIGR01377
      Location:5383
      soxA_mon; sarcosine oxidase, monomeric form
      cl21454
      Location:135
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins