C39B5.6 Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial [Caenorhabditis elegans] - Gene

Summary

Official Symbol: C39B5.6
Official Full Name: Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial
Primary source: WormBase:WBGene00016524
Locus tag: CELE_C39B5.6
See related: AllianceGenome:WB:WBGene00016524
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity. Predicted to be involved in glutaminyl-tRNAGln biosynthesis via transamidation and mitochondrial translation. Predicted to be part of glutamyl-tRNA(Gln) amidotransferase complex. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 41. Orthologous to human GATB (glutamyl-tRNA amidotransferase subunit B). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

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Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables carbon-nitrogen ligase activity, with glutamine as amido-N-donor	IEA Inferred from Electronic Annotation more info
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity	IBA Inferred from Biological aspect of Ancestor more info
enables glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity	IEA Inferred from Electronic Annotation more info
enables ligase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in glutaminyl-tRNAGln biosynthesis via transamidation	IBA Inferred from Biological aspect of Ancestor more info
involved_in glutaminyl-tRNAGln biosynthesis via transamidation	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial translation	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial translation	IEA Inferred from Electronic Annotation more info
involved_in translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of glutamyl-tRNA(Gln) amidotransferase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of glutamyl-tRNA(Gln) amidotransferase complex	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

Preferred Names: Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial

NP_497510.2

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The following sections contain reference sequences that belong to a specific genome build. Explain