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    M116.5 Calponin homology domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177642, updated on 9-Dec-2024

    Summary

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    Official Symbol
    M116.5
    Official Full Name
    Calponin homology domain-containing protein
    Primary source
    WormBase:WBGene00019792
    Locus tag
    CELE_M116.5
    See related
    AllianceGenome:WB:WBGene00019792
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable actin binding activity and microtubule binding activity. Predicted to be involved in actin cytoskeleton organization. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be part of filamentous actin. Predicted to be active in microtubule organizing center. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See M116.5 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    17
    Sequence:
    Chromosome: IV; NC_003282.8 (8414265..8421061, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene F-box domain-containing protein Neighboring gene F-box domain-containing protein Neighboring gene pseudo Neighboring gene Transthyretin-like family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Calponin homology domain-containing protein
    NP_501432.4
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      8414265..8421061 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069031.7 → NP_501432.4  Calponin homology domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501432.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q965L0
      Conserved Domains (3) summary
      smart00243
      Location:796 → 868
      GAS2; Growth-Arrest-Specific Protein 2 Domain
      cd21188
      Location:38 → 142
      CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
      cl00030
      Location:179 → 285
      CH_SF; calponin homology (CH) domain superfamily
    Nucleotide Protein
    Heading Accession and Version

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