W02H5.8 Triokinase/FMN cyclase [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: W02H5.8
Official Full Name: Triokinase/FMN cyclase
Primary source: WormBase:WBGene00020962
Locus tag: CELE_W02H5.8
See related: AllianceGenome:WB:WBGene00020962
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable glycerone kinase activity. Predicted to be involved in glycerol catabolic process. Predicted to be active in cytosol. Is expressed in intestine. Orthologous to human TKFC (triokinase and FMN cyclase). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See W02H5.8 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 5

Sequence:: Chromosome: V; NC_003283.11 (2647055..2652657, complement)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

W02H5.a (e-PCR)
- UniSTS:322631

W02H5.n (e-PCR)
- UniSTS:322638

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables FAD-AMP lyase (cyclizing) activity	IEA Inferred from Electronic Annotation more info
enables glycerone kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glycerone kinase activity	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables phosphotransferase activity, alcohol group as acceptor	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in glycerol catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in glycerol metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Triokinase/FMN cyclase

NP_503724.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

2647055..2652657 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_071323.7 → NP_503724.1 Triokinase/FMN cyclase [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_503724.1

Status: REVIEWED

UniProtKB/TrEMBL

Q9N5C4

Conserved Domains (3) summary

TIGR02361
Location:3 → 571

dak_ATP; dihydroxyacetone kinase, ATP-dependent

pfam02733
Location:19 → 328

Dak1; Dak1 domain

pfam02734
Location:394 → 569

Dak2; DAK2 domain