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    Y23H5B.5 U3 small nucleolar RNA-associated protein 15 homolog [ Caenorhabditis elegans ]

    Gene ID: 171811, updated on 4-Jan-2025

    Summary

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    Official Symbol
    Y23H5B.5
    Official Full Name
    U3 small nucleolar RNA-associated protein 15 homolog
    Primary source
    WormBase:WBGene00021276
    Locus tag
    CELE_Y23H5B.5
    See related
    AllianceGenome:WB:WBGene00021276
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in positive regulation of transcription by RNA polymerase I and rRNA processing. Predicted to be located in nucleus. Predicted to be active in nucleolus. Orthologous to human UTP15 (UTP15 small subunit processome component). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

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    See Y23H5B.5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    6
    Sequence:
    Chromosome: I; NC_003279.8 (2498134..2506259)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Eukaryotic translation initiation factor 3 subunit I;Serine-threonine kinase receptor-associated protein Neighboring gene ATP-dependent RNA helicase;ATP-dependent rRNA helicase SPB4-like C-terminal extension domain-containing protein Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase I IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    U3 small nucleolar RNA-associated protein 15 homolog
    NP_490990.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      2498134..2506259
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058589.5 → NP_490990.2  U3 small nucleolar RNA-associated protein 15 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_490990.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N477
      Conserved Domains (3) summary
      sd00039
      Location:44 → 80
      7WD40; WD40 repeat [structural motif]
      pfam09384
      Location:362 → 508
      UTP15_C; UTP15 C terminal
      cl29593
      Location:40 → 319
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version

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