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    Y37B11A.3 Citrate transport protein [ Caenorhabditis elegans ]

    Gene ID: 189611, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y37B11A.3
    Official Full Name
    Citrate transport protein
    Primary source
    WormBase:WBGene00021345
    Locus tag
    CELE_Y37B11A.3
    See related
    AllianceGenome:WB:WBGene00021345
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable citrate secondary active transmembrane transporter activity. Predicted to be involved in mitochondrial citrate transmembrane transport. Predicted to be located in membrane. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in 2-hydroxyglutaric aciduria; combined D-2- and L-2-hydroxyglutaric aciduria; and congenital myasthenic syndrome. Orthologous to human SLC25A1 (solute carrier family 25 member 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y37B11A.3 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    3
    Sequence:
    Chromosome: III; NC_003281.10 (5784358..5785322, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene DNA polymerase Neighboring gene tRNA-Gly Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DNA polymerase theta Neighboring gene Homeobox protein ceh-10

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables citrate secondary active transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial citrate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Citrate transport protein
    NP_498249.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      5784358..5785322 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065848.6 → NP_498249.3  Citrate transport protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9BKQ2
      Conserved Domains (1) summary
      pfam00153
      Location:29 → 95
      Mito_carr; Mitochondrial carrier protein
    Nucleotide Protein
    Heading Accession and Version

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