slc-36.1 Amino acid transporter transmembrane domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: slc-36.1
Official Full Name: Amino acid transporter transmembrane domain-containing protein
Primary source: WormBase:WBGene00012804
Locus tag: CELE_Y43F4B.7
See related: AllianceGenome:WB:WBGene00012804
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be located in membrane. Predicted to be active in vacuolar membrane. Is expressed in several structures, including anal depressor muscle; body wall musculature; germ line; intestine; and pharynx. Human ortholog(s) of this gene implicated in iminoglycinuria. Orthologous to several human genes including SLC36A1 (solute carrier family 36 member 1); SLC36A2 (solute carrier family 36 member 2); and SLC36A3 (solute carrier family 36 member 3). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See slc-36.1 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 13

Sequence:: Chromosome: III; NC_003281.10 (13307502..13313389)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Y43F4B.7 (e-PCR)
- UniSTS:319763

Y43F4B.6 (e-PCR)
- UniSTS:308178

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables L-amino acid transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in L-alpha-amino acid transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in amino acid transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in proline transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in vacuolar membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Amino acid transporter transmembrane domain-containing protein

NP_499743.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

13307502..13313389

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_067342.11 → NP_499743.2 Amino acid transporter transmembrane domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_499743.2

Status: REVIEWED

UniProtKB/TrEMBL

O45936

Conserved Domains (1) summary

cl00456
Location:50 → 445

SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain