Y50D4A.4 Mic1 domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: Y50D4A.4
Official Full Name: Mic1 domain-containing protein
Primary source: WormBase:WBGene00021738
Locus tag: CELE_Y50D4A.4
See related: AllianceGenome:WB:WBGene00021738
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be involved in regulation of autophagy. Predicted to be part of Mon1-Ccz1 complex. Predicted to be active in late endosome membrane. Orthologous to human RMC1 (regulator of MON1-CCZ1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See Y50D4A.4 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 9

Sequence:: Chromosome: V; NC_003283.11 (1184876..1196127, complement)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of autophagy	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of autophagy	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of Mon1-Ccz1 complex	IBA Inferred from Biological aspect of Ancestor more info
part_of Mon1-Ccz1 complex	IEA Inferred from Electronic Annotation more info
is_active_in late endosome membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Mic1 domain-containing protein

NP_001300262.1

Confirmed by transcript evidence

NP_001300263.1

Confirmed by transcript evidence

NP_503392.3

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

1184876..1196127 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_070991.9 → NP_503392.3 Mic1 domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_503392.3

Status: REVIEWED

UniProtKB/TrEMBL

Q95Y58

Conserved Domains (1) summary

pfam07035
Location:451 → 606

Mic1; Colon cancer-associated protein Mic1-like
NM_001313334.3 → NP_001300263.1 Mic1 domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A0K3AW32

Conserved Domains (1) summary

pfam07035
Location:262 → 417

Mic1; Colon cancer-associated protein Mic1-like
NM_001313333.3 → NP_001300262.1 Mic1 domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A0K3ASH4

Conserved Domains (1) summary

pfam07035
Location:116 → 271

Mic1; Colon cancer-associated protein Mic1-like