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    Olfr908 olfactory receptor 908 [ Mus musculus (house mouse) ]

    Gene ID: 258872, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Olfr908provided by MGI
    Official Full Name
    olfactory receptor 908provided by MGI
    Primary source
    MGI:MGI:3030742
    See related
    Ensembl:ENSMUSG00000110991 AllianceGenome:MGI:3030742
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MOR165-2
    Summary
    This olfactory receptor gene represents a polymorphic pseudogene, with both coding and noncoding alleles of this gene found in different mouse strains. The reference genome sequence encodes the noncoding allele. Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jan 2019]
    Annotation information
    Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.
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    Genomic context

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    See Olfr908 in Genome Data Viewer
    Location:
    9 A5.1; 9 20.84 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (38427330..38428261)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (38516034..38516965)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 8 subfamily B member 44 Neighboring gene predicted gene, 23271 Neighboring gene olfactory receptor family 8 subfamily B member 47 Neighboring gene olfactory receptor family 8 subfamily B member 46

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
    2. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
    3. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    olfactory receptor 908
    Names
    GA_x6K02T2PVTD-32216179-32217111
    olfactory receptor MOR165-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146872.1 → NP_667083.1  olfactory receptor 908

      See identical proteins and their annotated locations for NP_667083.1

      Status: VALIDATED

      Description
      Transcript Variant: This transcript represents the protein-coding allele present in some non-reference strains.
      Source sequence(s)
      AY073218
      UniProtKB/TrEMBL
      Q7TRC6, Q8VGD2
      Conserved Domains (2) summary
      pfam00001
      Location:41 → 290
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:34 → 306
      7tm_4; Olfactory receptor

    RNA

    1. NR_160700.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This transcript represents the noncoding allele present in the reference genome.
      Source sequence(s)
      AC069559
      Related
      ENSMUST00000215139.2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      38427330..38428261
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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