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    sfc6 transcription factor TFIIIC subunit Sfc6 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540424, updated on 18-Sep-2024

    Summary

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    Official Symbol
    sfc6
    Official Full Name
    transcription factor TFIIIC subunit Sfc6
    Primary source
    PomBase:SPBC21H7.05
    Locus tag
    SPOM_SPBC21H7.05
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See sfc6 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003423.3 (2262185..2264164)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ATP-dependent RNA helicase Dbp7 Neighboring gene ncRNA Neighboring gene 5S ribosomal RNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene hikeshi family nuclear import carrier Opi10

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A role for TFIIIC transcription factor complex in genome organization. Noma K, et al. Cell, 2006 Jun 2. PMID 16751097
    2. Isolation and cloning of four subunits of a fission yeast TFIIIC complex that includes an ortholog of the human regulatory protein TFIIICbeta. Huang Y, et al. J Biol Chem, 2000 Oct 6. PMID 10906331
    3. Interaction between TBP and Condensin Drives the Organization and Faithful Segregation of Mitotic Chromosomes. Iwasaki O, et al. Mol Cell, 2015 Sep 3. PMID 26257282, Free PMC Article
    4. CPF-associated phosphatase activity opposes condensin-mediated chromosome condensation. Vanoosthuyse V, et al. PLoS Genet, 2014 Jun. PMID 24945319, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA polymerase III general transcription initiation factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    contributes_to chromatin insulator sequence binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables tDNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in transcription by RNA polymerase III IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation at RNA polymerase III promoter IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    part_of transcription factor TFIIIC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFIIIC complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription factor TFIIIC subunit Sfc6

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2262185..2264164
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021838.3 → NP_595930.1  transcription factor TFIIIC subunit Sfc6 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595930.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O60174
      Conserved Domains (4) summary
      COG2319
      Location:42 → 500
      WD40; WD40 repeat [General function prediction only]
      pfam13257
      Location:34 → 95
      DUF4048; Domain of unknown function (DUF4048)
      sd00039
      Location:274 → 326
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:243 → 445
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version

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