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    RPL22B ribosomal 60S subunit protein L22B [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850509, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RPL22B
    Official Full Name
    ribosomal 60S subunit protein L22B
    Primary source
    SGD:S000006436
    Locus tag
    YFL034C-A
    See related
    AllianceGenome:SGD:S000006436; FungiDB:YFL034C-A; VEuPathDB:YFL034C-A
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    YFL035C-B
    Summary
    A structural constituent of ribosome. Involved in cytoplasmic translation. Part of cytosolic large ribosomal subunit. Orthologous to several human genes including RPL22L1 (ribosomal protein L22 like 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RPL22B in Genome Data Viewer
    Location:
    chromosome: VI
    Exon count:
    2
    Sequence:
    Chromosome: VI; NC_001138.5 (64243..64932, complement)

    Chromosome VI - NC_001138.5Genomic Context describing neighboring genes Neighboring gene DNA-directed RNA polymerase Neighboring gene Mob2p Neighboring gene Mil1p Neighboring gene protein kinase RIM15

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001138.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Conserved codon composition of ribosomal protein coding genes in Escherichia coli, Mycobacterium tuberculosis and Saccharomyces cerevisiae: lessons from supervised machine learning in functional genomics. Lin K, et al. Nucleic Acids Res, 2002 Jun 1. PMID 12034849, Free PMC Article
    2. Rpl22 is required for IME1 mRNA translation and meiotic induction in S. cerevisiae. Kim SJ, et al. Cell Div, 2016. PMID 27478489, Free PMC Article
    3. Introns provide a platform for intergenic regulatory feedback of RPL22 paralogs in yeast. Abrhámová K, et al. PLoS One, 2018. PMID 29304067, Free PMC Article
    4. Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins. Chan CT, et al. Nat Commun, 2012 Jul 3. PMID 22760636, Free PMC Article
    5. Translational control of one-carbon metabolism underpins ribosomal protein phenotypes in cell division and longevity. Maitra N, et al. Elife, 2020 May 20. PMID 32432546, Free PMC Article

    See all (50) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cytoplasmic translation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in cytoplasmic translation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 60S subunit protein L22B
    NP_116619.1
    • Ribosomal 60S subunit protein L22A; required for translation of long 5' UTR of IME1 mRNA and meiotic entry; autoregulates splicing of its pre-m-RNA; homologous to mammalian ribosomal protein L22, no bacterial homolog; RPL22B has a paralog, RPL22A, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001138.5 Reference assembly

      Range
      64243..64932 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184310.1 → NP_116619.1  TPA: ribosomal 60S subunit protein L22B [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_116619.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VTJ6, P56628
      UniProtKB/TrEMBL
      A7A205, B3LUH7, C8Z7P8, G2WDA7, N1PA18
      Conserved Domains (1) summary
      pfam01776
      Location:16 → 110
      Ribosomal_L22e; Ribosomal L22e protein family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P56628.2

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