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    spc24 protein Spc24 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540238, updated on 18-Sep-2024

    Summary

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    Official Symbol
    spc24
    Official Full Name
    protein Spc24
    Primary source
    PomBase:SPBC336.08
    Locus tag
    SPOM_SPBC336.08
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See spc24 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (2755426..2759388)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene transcription factor TFIIIC subunit Sfc3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RNA polymerase I general transcription initiation factor subunit Rrn7 Neighboring gene putative translation elongation factor eIF5A Neighboring gene GARP complex subunit Vps52 Neighboring gene ncRNA Neighboring gene DNA-binding transcription factor, MBF transcription factor complex subunit Cdc10

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Purification and characterisation of the fission yeast Ndc80 complex. Matsuo Y, et al. Protein Expr Purif, 2017 Jul. PMID 28502666, Free PMC Article
    2. Dissociation of the Nuf2-Ndc80 complex releases centromeres from the spindle-pole body during meiotic prophase in fission yeast. Asakawa H, et al. Mol Biol Cell, 2005 May. PMID 15728720, Free PMC Article
    3. The fission yeast kinetochore component Spc7 associates with the EB1 family member Mal3 and is required for kinetochore-spindle association. Kerres A, et al. Mol Biol Cell, 2004 Dec. PMID 15371542, Free PMC Article
    4. The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation. Wigge PA, et al. J Cell Biol, 2001 Jan 22. PMID 11266451, Free PMC Article
    5. Mad1 contribution to spindle assembly checkpoint signalling goes beyond presenting Mad2 at kinetochores. Heinrich S, et al. EMBO Rep, 2014 Mar. PMID 24477934, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    contributes_to microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to microtubule binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromosome segregation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in meiotic centromere clustering EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in mitotic sister chromatid segregation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in sister chromatid biorientation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in spindle attachment to meiosis I kinetochore IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of Ndc80 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Ndc80 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in chromosome, centromeric region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in condensed chromosome, centromeric region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IC
    Inferred by Curator
    more info
    		  

    General protein information

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    Preferred Names
    protein Spc24

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2755426..2759388
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022046.3 → NP_596128.1  protein Spc24 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596128.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9UST6
      Conserved Domains (1) summary
      pfam08286
      Location:84 → 190
      Spc24; Spc24 subunit of Ndc80
    Nucleotide Protein
    Heading Accession and Version

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