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    pst1 Clr6 I prime and Rpd3L histone deacetylase complex subunit Pst1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540018, updated on 14-Nov-2024

    Summary

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    Official Symbol
    pst1
    Official Full Name
    Clr6 I prime and Rpd3L histone deacetylase complex subunit Pst1
    Primary source
    PomBase:SPBC12C2.10c
    Locus tag
    SPOM_SPBC12C2.10C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPBC21D10.01c
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    Genomic context

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    See pst1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003423.3 (2452028..2457119)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene glutamine-fructose-6-phosphate transaminase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene hemolysin-III family protein Neighboring gene mitochondrial dynamin family scission GTPase Dnm1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new member of the Sin3 family of corepressors is essential for cell viability and required for retroelement propagation in fission yeast. Dang VD, et al. Mol Cell Biol, 1999 Mar. PMID 10022921, Free PMC Article
    2. A new role for the transcriptional corepressor SIN3; regulation of centromeres. Silverstein RA, et al. Curr Biol, 2003 Jan 8. PMID 12526748
    3. Distinct roles of HDAC complexes in promoter silencing, antisense suppression and DNA damage protection. Nicolas E, et al. Nat Struct Mol Biol, 2007 May. PMID 17450151
    4. Two assembly modes for SIN3 histone deacetylase complexes. Wang C, et al. Cell Discov, 2023 Apr 19. PMID 37076472, Free PMC Article
    5. Rbm10 facilitates heterochromatin assembly via the Clr6 HDAC complex. Weigt M, et al. Epigenetics Chromatin, 2021 Jan 19. PMID 33468217, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription corepressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in pericentric heterochromatin formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transcription initiation-coupled chromatin remodeling IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of Rpd3L complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of Rpd3L-Expanded complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of Sin3-type complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in pericentric heterochromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Clr6 I prime and Rpd3L histone deacetylase complex subunit Pst1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2452028..2457119
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021920.3 → NP_596012.2  Clr6 I prime and Rpd3L histone deacetylase complex subunit Pst1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596012.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q09750
      Conserved Domains (4) summary
      smart00761
      Location:592 → 693
      HDAC_interact; Histone deacetylase (HDAC) interacting
      COG5602
      Location:42 → 1315
      Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]
      pfam02671
      Location:201 → 245
      PAH; Paired amphipathic helix repeat
      pfam16879
      Location:1004 → 1282
      Sin3a_C; C-terminal domain of Sin3a protein
    Nucleotide Protein
    Heading Accession and Version

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