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    srb6 mediator complex subunit Med22 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542413, updated on 18-Sep-2024

    Summary

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    Official Symbol
    srb6
    Official Full Name
    mediator complex subunit Med22
    Primary source
    PomBase:SPAC29A4.07
    Locus tag
    SPOM_SPAC29A4.07
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    med22
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    Genomic context

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    See srb6 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (5133784..5136019, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene rRNA exonuclease Rrp17 Neighboring gene ncRNA Neighboring gene Prp19 complex subunit, ubiquitin-protein ligase E4 Prp19 Neighboring gene splicing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene myosin I light chain Cam2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure of the Mediator head module. Larivière L, et al. Nature, 2012 Dec 20. PMID 23123849
    2. Purification and characterization of RNA polymerase II holoenzyme from Schizosaccharomyces pombe. Spåhr H, et al. J Biol Chem, 2000 Jan 14. PMID 10625684
    3. Mediator is required for activated transcription in a Schizosaccharomyces pombe in vitro system. Tamayo E, et al. Eur J Biochem, 2004 Jun. PMID 15182371
    4. Core Mediator structure at 3.4 Å extends model of transcription initiation complex. Nozawa K, et al. Nature, 2017 May 11. PMID 28467824
    5. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription coactivator activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables transcription coactivator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of transcription initiation by RNA polymerase II EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in transcription initiation at RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mediator complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    mediator complex subunit Med22

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      5133784..5136019 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020304.3 → NP_594875.1  mediator complex subunit Med22 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594875.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14010
      Conserved Domains (1) summary
      pfam06179
      Location:21 → 116
      Med22; Surfeit locus protein 5 subunit 22 of Mediator complex
    Nucleotide Protein
    Heading Accession and Version

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