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    cwh43 glycosylceramide biosynthesis protein [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542152, updated on 18-Sep-2024

    Summary

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    Official Symbol
    cwh43
    Official Full Name
    glycosylceramide biosynthesis protein
    Primary source
    PomBase:SPAC589.12
    Locus tag
    SPOM_SPAC589.12
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPAC688.01
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    Genomic context

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    See cwh43 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (3110201..3113396)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene sec14 family protein Neighboring gene ncRNA Neighboring gene ubiquitin-40S ribosomal protein S31 fusion protein Neighboring gene translation release factor Neighboring gene ncRNA Neighboring gene AMMECR1 family protein Neighboring gene MIS12/MIND complex Mis14/Nsl1 Neighboring gene glutathione S-transferase Gst3 Neighboring gene structure-specific endonuclease subunit Slx4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Coordinated Roles of the Putative Ceramide-Conjugation Protein, Cwh43, and a Mn(2+)-Transporting, P-Type ATPase, Pmr1, in Fission Yeast. Nakazawa N, et al. G3 (Bethesda), 2019 Aug 8. PMID 31201205, Free PMC Article
    2. The putative ceramide-conjugation protein Cwh43 regulates G0 quiescence, nutrient metabolism and lipid homeostasis in fission yeast. Nakazawa N, et al. J Cell Sci, 2018 Aug 21. PMID 30072439
    3. Inner nuclear membrane proteins Lem2 and Bqt4 interact with different lipid synthesis enzymes in fission yeast. Hirano Y, et al. J Biochem, 2023 Jun 30. PMID 36799444
    4. The fission yeast nucleoporin Alm1 is required for proteasomal degradation of kinetochore components. Salas-Pino S, et al. J Cell Biol, 2017 Nov 6. PMID 28974540, Free PMC Article
    5. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in GPI anchor biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in fungal-type cell wall organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum HDA PubMed 
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in perinuclear endoplasmic reticulum membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    is_active_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glycosylceramide biosynthesis protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3110201..3113396
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019484.2 → NP_594060.2  glycosylceramide biosynthesis protein [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594060.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P78781, Q9HDZ2, Q9P6M4
      Conserved Domains (2) summary
      pfam10277
      Location:11 → 220
      Frag1; Frag1/DRAM/Sfk1 family
      cl00490
      Location:727 → 874
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily
    Nucleotide Protein
    Heading Accession and Version

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