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    cig2 G1/S-specific B-type cyclin Cig2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543481, updated on 18-Sep-2024

    Summary

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    Official Symbol
    cig2
    Official Full Name
    G1/S-specific B-type cyclin Cig2
    Primary source
    PomBase:SPAPB2B4.03
    Locus tag
    SPOM_SPAPB2B4.03
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    cyc17
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    Genomic context

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    See cig2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (2709782..2714162)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene mitochondrial [2Fe-2S] cluster assembly and transfer glutaredoxin Grx5 Neighboring gene ncRNA Neighboring gene P2 type calcium transporting P-type ATPase Pmc1 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The fission yeast S-phase cyclin Cig2 can drive mitosis. Pickering M, et al. Genetics, 2021 Mar 3. PMID 33683349, Free PMC Article
    2. Roles of Wee1 and Nim1 protein kinases in regulating the switch from mitotic division to sexual development in Schizosaccharomyces pombe. Wu L, et al. Mol Cell Biol, 1997 Jan. PMID 8972180, Free PMC Article
    3. Regulation of G1 progression in fission yeast by the rum1+ gene product. Martín-Castellanos C, et al. Prog Cell Cycle Res, 1996. PMID 9552380
    4. A meiosis-specific cyclin regulated by splicing is required for proper progression through meiosis. Malapeira J, et al. Mol Cell Biol, 2005 Aug. PMID 16024772, Free PMC Article
    5. Cyclin B proteolysis and the cyclin-dependent kinase inhibitor rum1p are required for pheromone-induced G1 arrest in fission yeast. Stern B, et al. Mol Biol Cell, 1998 Jun. PMID 9614176, Free PMC Article

    See all (46) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables cyclin-dependent protein serine/threonine kinase activator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables cyclin-dependent protein serine/threonine kinase activator activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables cyclin-dependent protein serine/threonine kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA recombination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in G1/S transition of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic G1 cell size control checkpoint signaling IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in negative regulation of conjugation with cellular fusion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of G1/S transition of mitotic cell cycle IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in positive regulation of G1/S transition of mitotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of cell cycle switching, mitotic to meiotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in traversing start control point of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in traversing start control point of mitotic cell cycle IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cyclin-dependent protein kinase holoenzyme complex EXP
    Inferred from Experiment
    more info
    		 PubMed 
    part_of cyclin-dependent protein kinase holoenzyme complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in microtubule organizing center IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitotic spindle pole body HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    G1/S-specific B-type cyclin Cig2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2709782..2714162
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019319.3 → NP_593889.1  G1/S-specific B-type cyclin Cig2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593889.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P36630
      Conserved Domains (3) summary
      COG5024
      Location:1 → 399
      COG5024; Cyclin [Cell division and chromosome partitioning]
      pfam00134
      Location:139 → 265
      Cyclin_N; Cyclin, N-terminal domain
      pfam02984
      Location:267 → 382
      Cyclin_C; Cyclin, C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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