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    sepiapterin reductase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540402, updated on 18-Sep-2024

    Summary

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    Official Full Name
    sepiapterin reductase
    Primary source
    PomBase:SPBC30D10.05c
    Locus tag
    SPOM_SPBC30D10.05C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (3089927..3090914)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene biotin-protein ligase Neighboring gene U6 snRNP-associated protein Lsm4 Neighboring gene ncRNA Neighboring gene chaperone protein Mzm1 Neighboring gene ncRNA Neighboring gene replication fork protection complex subunit Swi3 Neighboring gene IMP 5'-nucleotidase Neighboring gene ncRNA Neighboring gene transcription corepressor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways. Das J, et al. Sci Signal, 2013 May 21. PMID 23695164, Free PMC Article
    2. A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors. Chen Z, et al. G3 (Bethesda), 2012 Oct. PMID 23050226, Free PMC Article
    3. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
    4. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sepiapterin reductase (NADP+) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in tetrahydrobiopterin biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    sepiapterin reductase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3089927..3090914
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022201.3 → NP_596280.1  sepiapterin reductase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596280.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14351
      Conserved Domains (2) summary
      cd05367
      Location:8 → 245
      SPR-like_SDR_c; sepiapterin reductase (SPR)-like, classical (c) SDRs
      pfam00106
      Location:7 → 190
      adh_short; short chain dehydrogenase
    Nucleotide Protein
    Heading Accession and Version

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