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    hrr1 helicase Hrr1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539248, updated on 14-Nov-2024

    Summary

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    Official Symbol
    hrr1
    Official Full Name
    helicase Hrr1
    Primary source
    PomBase:SPCC1739.03
    Locus tag
    SPOM_SPCC1739.03
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See hrr1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    4
    Sequence:
    Chromosome: III; NC_003421.2 (2029460..2034205)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene zf-CCCH type zinc finger protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene mitochondrial 54S ribosomal protein uL22m Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein Dms1 Neighboring gene ncRNA Neighboring gene histone lysine methyltransferase Set5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A conserved ncRNA-binding protein recruits silencing factors to heterochromatin through an RNAi-independent mechanism. Marina DB, et al. Genes Dev, 2013 Sep 1. PMID 24013500, Free PMC Article
    2. Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs. Motamedi MR, et al. Cell, 2004 Dec 17. PMID 15607976
    3. Heterochromatin protein 1 homologue Swi6 acts in concert with Ers1 to regulate RNAi-directed heterochromatin assembly. Hayashi A, et al. Proc Natl Acad Sci U S A, 2012 Apr 17. PMID 22474355, Free PMC Article
    4. Conserved protein Pir2(ARS2) mediates gene repression through cryptic introns in lncRNAs. Thillainadesan G, et al. Nat Commun, 2020 May 15. PMID 32415063, Free PMC Article
    5. Ers1 links HP1 to RNAi. Rougemaille M, et al. Proc Natl Acad Sci U S A, 2012 Jul 10. PMID 22733737, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA helicase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables lncRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulatory ncRNA-mediated heterochromatin formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in siRNA-mediated pericentric heterochromatin formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA-directed RNA polymerase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    part_of nuclear RNA-directed RNA polymerase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of nuclear RNA-directed RNA polymerase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    helicase Hrr1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      2029460..2034205
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023402.3 → NP_588411.2  helicase Hrr1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588411.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74465
      Conserved Domains (3) summary
      COG1112
      Location:158 → 965
      DNA2; Superfamily I DNA and/or RNA helicase [Replication, recombination and repair]
      pfam13087
      Location:757 → 942
      AAA_12; AAA domain
      pfam13245
      Location:387 → 446
      AAA_19; Part of AAA domain
    Nucleotide Protein
    Heading Accession and Version

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